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Tyrosine 3-Monooxygenase
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Definition of 'Tyrosine 3-Monooxygenase'

An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-L-phenylalanine, dihydrobiopterin, and water. EC 1.14.16.2.

Common names: Tyrosine 3-Monooxygenase; 3-Monooxygenase, Tyrosine; Tyrosine 3 Monooxygenase; Tyrosine Hydroxylase; Hydroxylase, Tyrosine

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Saturday, November 21, 2009

Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells.

29 Sep 2009 Local synapses formed by nondopamine cells within the ventral tegmental area (VTA) are thought to provide an important regulatory influence on the activity patterns of dopamine (DA) neurons. However, ultrastructural confirmation of intra-areal ... Read more...


The human insulin gene is part of a large open chromatin domain specific for human islets.

26 Sep 2009 Knowledge of how insulin (INS) gene expression is regulated will lead to better understanding of normal and abnormal pancreatic beta cell function. We have mapped histone modifications over the INS region, coupled with an expression profile, in ... Read more...


The dopaminergic system of the telencephalo-diencephalic areas of the vertebrate brain in the organization of the sleep-waking cycle.

21 Sep 2009 The aim of the present work was to study the involvement of the dopaminergic system of the telencephalic and diencephalic areas of the vertebrate brain in the organization of the sleep-waking cycle in cold-blooded and warm-blooded vertebrates. ... Read more...

 

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Technical information about 'Tyrosine 3-Monooxygenase'

Definition: An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-L-phenylalanine, dihydrobiopterin, and water. EC 1.14.16.2.

Chemical name: L-Tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)

Registry Number: EC 1.14.16.2

Descriptor UI: D014446

Alternative terms: Tyrosine 3-Monooxygenase; 3-Monooxygenase, Tyrosine; Tyrosine 3 Monooxygenase; Tyrosine Hydroxylase; Hydroxylase, Tyrosine;

Allowable Qualifiers: pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics;

Tree Number: D08.811.682.690.708.923; D12.776.556.579.374.925;

Online Note: use TYROSINE 3-MONOOXYGENASE to search TYROSINE HYDROXYLASE 1971-94 (as Prov 1971-73)

History Note: 95; was TYROSINE HYDROXYLASE 1971-94 (Prov 1971-73)

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