Up-Regulation
Research News and Information

Monday, March 22, 2010

Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response.

29 Nov 2009 Following our recent findings on the presence of human cytomegalovirus (HCMV) in the normal human adrenal cortex and in adrenocortical tumors, especially in cortisol-secreting tumors, aim of the present study was to investigate the direct effects of ... Read more...

Identification of genes associated with progression and metastasis of advanced cervical cancers after radiotherapy by cDNA microarray analysis.

13 Nov 2009 PURPOSE: To identify a set of genes related to the progression and metastasis of advanced cervical cancer after radiotherapy and to establish a predictive method. METHODS AND MATERIALS: A total of 28 patients with cervical cancer (15 stage IIIB, 13 ... Read more...

Physiologic cold shock increases adherence of Moraxella catarrhalis to and secretion of interleukin 8 in human upper respiratory tract epithelial cells.

13 Nov 2009 Moraxella catarrhalis, a major nasopharyngeal pathogen of the human respiratory tract, is exposed to rapid and prolonged downshifts of environmental temperature when humans breathe cold air. In the present study, we show that a 26 degrees C cold ... Read more...

Latest indexed articles for 'Up-Regulation'

These are the very latest articles for this heading:

• Human cytomegalovirus productively infects adrenocortical cells and induces an early cortisol response. 29 Nov 2009
• Identification of genes associated with progression and metastasis of advanced cervical cancers after radiotherapy by cDNA microarray analysis. 13 Nov 2009
• Physiologic cold shock increases adherence of Moraxella catarrhalis to and secretion of interleukin 8 in human upper respiratory tract epithelial cells. 13 Nov 2009
• Expression and role of CXCL10 during the encephalitic stage of experimental and clinical African trypanosomiasis. 13 Nov 2009
• In vivo major histocompatibility complex class I (MHCI) expression on MHCIlow tumor cells is regulated by gammadelta T and NK cells during the early steps of tumor growth. 31 Oct 2009
• Attenuation of subarachnoid hemorrhage-induced apoptotic cell death with 17 beta-estradiol. Laboratory investigation. 30 Oct 2009
• Equal contribution of increased intracranial pressure and subarachnoid blood to cerebral blood flow reduction and receptor upregulation after subarachnoid hemorrhage. Laboratory investigation. 30 Oct 2009
• Interaction of B7-H1 on intrahepatic cholangiocarcinoma cells with PD-1 on tumor-infiltrating T cells as a mechanism of immune evasion. 30 Oct 2009
• The IL-8 production by Streptococcal pyrogenic exotoxin B. 30 Oct 2009
• Additive effects of hyperbaric oxygen and platelet-derived growth factor-BB in chondrocyte transplantation via up-regulation expression of platelet-derived growth factor-beta receptor. 30 Oct 2009
• The effect of a thoracic spinal block on fos expression in the lumbar spinal cord of the rat induced by a noxious electrical stimulus at the hindpaw. 30 Oct 2009
• Association of polymorphisms in regulatory regions of interleukin-12p40 gene and cytokine serum level with colorectal cancer. 30 Oct 2009
• Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma. 30 Oct 2009
• Upregulated p27kip1 can downregulate survivin expression and inhibit telomerase activity in gastric carcinoma cells. 30 Oct 2009
• Involvement of cytosolic phospholipase A2alpha in MMP-9 up-regulation. 30 Oct 2009
• TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors. 30 Oct 2009
• Upregulation of plakophilin-2 and its acquisition to adherens junctions identifies a novel molecular ensemble of cell-cell-attachment characteristic for transformed mesenchymal cells. 30 Oct 2009
• NAG7 promotes human nasopharyngeal carcinoma invasion through inhibition of estrogen receptor alpha and up-regulation of JNK2/AP-1/MMP1 pathways. 30 Oct 2009
• Upregulation of peroxisome proliferator-activated receptor-gamma and NADPH oxidases are involved in restenosis after balloon injury. 30 Oct 2009
• A perspective on challenges and issues in biomarker development and drug and biomarker codevelopment. 21 Oct 2009

See a longer list of these articles.

Technical information about 'Up-Regulation'

Definition: A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

Descriptor UI: D015854

Alternative terms: Up-Regulation; Up Regulation; Upregulation; Up-Regulation (Physiology); Receptor Up-Regulation;

Related Mesh Headings: Down-Regulation; Feedback, Biochemical;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G02.111.087.880; G02.149.115.880; G05.355.315.850; G07.690.812.925; G07.700.360.487.750; G07.700.680.925;

History Note: 2002 (1990)

Technical Notes: DF: UP REG