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Vascular Endothelial Growth Factor A - Analysis
Research News and Information
Definition of 'Vascular Endothelial Growth Factor A'The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced. |
Tuesday, November 24, 2009
VEGF expression as a prognostic marker in osteosarcoma.
29 Nov 2009 
BACKGROUND: The vascular endothelial growth factor (VEGF) pathway is the key regulator of angiogenesis. In osteosarcoma baseline VEGF is of proven prognostic value but prognostic potential of post-NACT VEGF expression is largely unexplored. ... Read more...
Anti-angiogenic factor endostatin in osteosarcoma.
29 Sep 2009 Neoplastic neovascularization is regulated not only by stimulators, but also by inhibitors of angiogenesis and might be the result of a net balance between the positive and negative regulators. Endostatin (ES) is a potent inhibitor of angiogenesis. ... Read more...
30 Aug 2009 BACKGROUND: Vascular endothelial growth factor (VEGF) has been implicated in tumorigenesis and metastasis, and it presumably mediates the proliferation of endothelial cells and promotes vascular permeability. However, the prognostic value of VEGF ... Read more...
Latest indexed articles for 'Vascular Endothelial Growth Factor A - Analysis'
These are the very latest articles for this heading:
- VEGF expression as a prognostic marker in osteosarcoma. 29 Nov 2009
- Anti-angiogenic factor endostatin in osteosarcoma. 29 Sep 2009
- Prognostic value of vascular endothelial growth factor expression in patients with lung cancer: a systematic review with meta-analysis. 30 Aug 2009
- Angiogenic signaling triggered by cariogenic bacteria in pulp cells. 30 Aug 2009
- CLIC4 mediates TGF-beta1-induced fibroblast-to-myofibroblast transdifferentiation in ovarian cancer. 30 Aug 2009
- Expression of VEGF and VEGF receptors in childhood precursor B-cell acute lymphoblastic leukemia evaluated by immunohistochemistry. 30 Aug 2009
- Monotherapy with thalidomide for treatment of spinal cord hemangioblastomas in a patient with von Hippel-Lindau disease. 30 Aug 2009
- Compressive force induces VEGF production in periodontal tissues. 30 Jul 2009
- Prognostic significance of periodic acid-Schiff-positive patterns in clear cell renal cell carcinoma. 30 Jul 2009
- Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities. 30 Jul 2009
- Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models. 30 Jul 2009
- Anterior diffuse retinoblastoma: mutational analysis and immunofluorescence staining. 30 Jul 2009
- CD147 and VEGF expression in advanced renal cell carcinoma and their prognostic value. 30 Jul 2009
- Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma. 26 Jul 2009
- Polymorphism of the manganese superoxide dismutase gene but not of vascular endothelial growth factor gene is a risk factor for diabetic retinopathy. 21 Jul 2009
- The antiangiogenic agent ZD4190 prevents tumour outgrowth in a model of minimal residual carcinoma in deep tissues. 19 Jul 2009
- Development of a fluorescent peptide for the detection of vascular endothelial growth factor (VEGF).
18 Jul 2009 - Reduction of Stat3 activity attenuates HIV-induced kidney injury. 14 Jul 2009
- Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice. 11 Jul 2009
- Development of a CE-MS method to analyze components of the potential biomarker vascular endothelial growth factor 165. 29 Jun 2009
See a longer list of these articles.
Technical information about 'Vascular Endothelial Growth Factor A'
Definition: The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
Registry Number: 0
Descriptor UI: D042461
Alternative terms: Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor-A; Vascular Permeability Factor; Permeability Factor, Vascular; VEGF; VEGF-A; Vascular Endothelial Growth Factor; Vasculotropin; Glioma-Derived Vascular Endothelial Cell Growth Factor; Glioma Derived Vascular Endothelial Cell Growth Factor; GD-VEGF;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D12.644.276.100.800.200; D12.776.467.100.800.200; D23.529.100.800.200;
History Note: 2004; use VASCULAR ENDOTHELIAL GROWTH FACTOR A (NM) 2000-2002