Vascular Endothelial Growth Factor Receptor-1 - Analysis
Research News and Information

Sunday, November 22, 2009

Expression of VEGF and VEGF receptors in childhood precursor B-cell acute lymphoblastic leukemia evaluated by immunohistochemistry.

30 Aug 2009 Perturbation in the expression and signaling pathways of vascular endothelial growth factor (VEGF) has been linked to pathogenesis of hematologic malignancies. We investigated the expression and clinical importance of VEGF and two of its receptors, ... Read more...

Analysis of in situ and ex vivo vascular endothelial growth factor receptor expression during experimental aortic aneurysm progression.

30 Jun 2009 OBJECTIVE: Mural inflammation and neovascularization are characteristic pathological features of abdominal aortic aneurysm (AAA) disease. Vascular endothelial growth factor receptor (VEGFR) expression may also mediate AAA growth and rupture. We ... Read more...

Copper-induced regression of cardiomyocyte hypertrophy is associated with enhanced vascular endothelial growth factor receptor-1 signalling pathway.

17 Jun 2009 AIMS: Vascular endothelial growth factor (VEGF) has been well documented to stimulate cell proliferation and differentiation; however, we have observed that copper (Cu)-induced regression of heart hypertrophy was VEGF-dependent. The present study ... Read more...

Latest indexed articles for 'Vascular Endothelial Growth Factor Receptor-1 - Analysis'

These are the very latest articles for this heading:

• Expression of VEGF and VEGF receptors in childhood precursor B-cell acute lymphoblastic leukemia evaluated by immunohistochemistry. 30 Aug 2009
• Analysis of in situ and ex vivo vascular endothelial growth factor receptor expression during experimental aortic aneurysm progression. 30 Jun 2009
• Copper-induced regression of cardiomyocyte hypertrophy is associated with enhanced vascular endothelial growth factor receptor-1 signalling pathway. 17 Jun 2009
• Generalized ROC curve inference for a biomarker subject to a limit of detection and measurement error. 13 Jun 2009
• Soluble vascular endothelial growth factor receptor 1 in tracheal aspirate fluid of preterm neonates at birth may be predictive of bronchopulmonary dysplasia/chronic lung disease. 30 May 2009
• Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1. 29 Apr 2009
• Angiogenesis inhibition causes hypertension and placental dysfunction in a rat model of preeclampsia. 30 Mar 2009
• Comparative study of human colonic tumor-derived endothelial cells (HCTEC) and normal colonic microvascular endothelial cells (HCMEC): Hypoxia-induced sVEGFR-1 and sVEGFR-2 levels. 30 Mar 2009
• Differential analyses of angiogenesis and expression of growth factors in micro- and macrovascular endothelial cells of type 2 diabetic rats. 14 Dec 2008
• Novel soluble Flt-1 isoforms in plasma and cultured placental explants from normotensive pregnant and preeclamptic women. 15 Nov 2008
• Distribution of VEGF and flt-1 in the normal dog tissues. 30 Oct 2008
• Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions. 30 Oct 2008
• Secretion of MMP-2 and MMP-9 induced by VEGF autocrine loop correlates with clinical features in childhood acute lymphoblastic leukemia. 29 Sep 2008
• Co-expression of receptor tyrosine kinases in esophageal adenocarcinoma and squamous cell cancer. 29 Sep 2008
• Impact of VEGF and VEGF receptor 1 (FLT1) expression on the prognosis of stage III esophageal cancer patients after radiochemotherapy. 30 Jul 2008
• Differentiation potential of human pancreatic stem cells for epithelial- and endothelial-like cell types. 7 Jul 2008
• Advances in anatomic, functional, and molecular imaging of angiogenesis. 30 Mar 2008
• Microvessel density and VEGF/VEGF receptor status and their role in sarcomas of the pulmonary artery. 30 Jan 2008
• VEGF and VEGFR-1 are coexpressed by epithelial and stromal cells of renal cell carcinoma. 13 Jan 2008
• A comparison of plasma versus histologic indices of angiogenic markers in breast cancer. 29 Nov 2007

See a longer list of these articles.

Technical information about 'Vascular Endothelial Growth Factor Receptor-1'

Definition: A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.

Registry Number: EC 2.7.1.112

Descriptor UI: D040281

Alternative terms: Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor 1; FLT1 Receptor Tyrosine Kinase; VEGF Receptor flt-1 Protein; VEGF Receptor flt 1 Protein; VEGFR-1; fms-Like Tyrosine Kinase; Tyrosine Kinase, fms-Like; Proto-Oncogene Protein flt; Proto Oncogene Protein flt; FLT1 RTK; VEGF Receptor, FLT; FLT VEGF Receptor; Receptor, FLT VEGF;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D08.811.913.696.620.682.725.400.950.100; D12.776.543.750.060.750.100; D12.776.543.750.750.400.910.100;

History Note: 2003; use VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 (NM) 1990-2002; for FLK-1 RECEPTOR TYROSINE KINASE use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1993-2002