Ventral Tegmental Area - Cytology
Research News and Information

Sunday, November 22, 2009

The time course of dopamine transmission in the ventral tegmental area.

19 Oct 2009 Synaptic transmission mediated by G-protein coupled receptors (GPCR) is not generally thought to be point-to-point. To determine the extent over which dopamine signals in the midbrain, the present study examined the concentration and time course of ... Read more...

Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells.

29 Sep 2009 Local synapses formed by nondopamine cells within the ventral tegmental area (VTA) are thought to provide an important regulatory influence on the activity patterns of dopamine (DA) neurons. However, ultrastructural confirmation of intra-areal ... Read more...

Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.

30 Jul 2009 The lateral hypothalamic area (LHA) acts in concert with the ventral tegmental area (VTA) and other components of the mesolimbic dopamine (DA) system to control motivation, including the incentive to feed. The anorexigenic hormone leptin modulates ... Read more...

Latest indexed articles for 'Ventral Tegmental Area - Cytology'

These are the very latest articles for this heading:

• The time course of dopamine transmission in the ventral tegmental area. 19 Oct 2009
• Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells. 29 Sep 2009
• Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. 30 Jul 2009
• Optical imaging of rat prefrontal neuronal activity evoked by stimulation of the ventral tegmental area. 15 Jun 2009
• The neurokinin-3 (NK3) and the neurokinin-1 (NK1) receptors are differentially targeted to mesocortical and mesolimbic projection neurons and to neuronal nuclei in the rat ventral tegmental area. 30 May 2009
• Sensitization of ventral tegmental area dopamine neurons to the stimulating effects of ethanol. 24 May 2009
• Chronic cocaine enhances corticotropin-releasing factor-dependent potentiation of excitatory transmission in ventral tegmental area dopamine neurons. 18 May 2009
• Bifeprunox and aripiprazole suppress in vivo VTA dopaminergic neuronal activity via D2 and not D3 dopamine autoreceptor activation. 16 May 2009
• Differential effects of dopamine D2 and GABA(A) receptor antagonists on dopamine neurons between the anterior and posterior ventral tegmental area of female Wistar rats. 29 Apr 2009
• The orbitofrontal cortex and ventral tegmental area are necessary for learning from unexpected outcomes. 28 Apr 2009
• Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. 21 Apr 2009
• Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. 3 Apr 2009
• Cocaine-induced LTP in the ventral tegmental area: new insights into mechanism and time course illuminate the cellular substrates of addiction. 16 Mar 2009
• Adrenergic and noradrenergic innervation of the midbrain ventral tegmental area and retrorubral field: prominent inputs from medullary homeostatic centers. 16 Mar 2009
• Activity of neurochemically heterogeneous dopaminergic neurons in the substantia nigra during spontaneous and driven changes in brain state. 2 Mar 2009
• The anorexic agents, sibutramine and fenfluramine, depress GABA(B)-induced inhibitory postsynaptic potentials in rat mesencephalic dopaminergic cells. 27 Feb 2009
• The intricacies of dopamine neuron modulation. 13 Jan 2009
• Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80. 15 Dec 2008
• Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptors. 15 Dec 2008
• Effects of endurance exercise on ventral tegmental area neurons in the chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and probenecid-treated mice. 4 Dec 2008

See a longer list of these articles.

Technical information about 'Ventral Tegmental Area'

Definition: A region in the mesencephalon which is dorsomedial to the substantia nigra and ventral to the red nucleus. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the nucleus accumbens. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of schizophrenia.

Descriptor UI: D017557

Alternative terms: Ventral Tegmental Area; Tegmental Area, Ventral;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.132.659.822.820; A08.186.211.653.822.820;

History Note: 94

Technical Notes: a region in the mesencephalon