Vitamin A - Metabolism
Research News and Information

Tuesday, November 24, 2009

Impact of micronutrient deficiencies on obesity.

29 Sep 2009 Micronutrient deficiencies have been found in obese individuals across age groups worldwide. While the effects of micronutrient deficiencies on human functions have been studied widely in different populations, there is limited information on how ... Read more...

N-terminal aliphatic residues dictate the structure, stability, assembly, and small molecule binding of the coiled-coil region of cartilage oligomeric matrix protein.

13 Sep 2009 The coiled-coil domain of cartilage oligomeric matrix protein (COMPcc) assembles into a homopentamer that naturally recognizes the small molecule 1,25-dihydroxyvitamin D(3) (vit D). To identify the residues critical for the structure, stability, ... Read more...

Application of a key events dose-response analysis to nutrients: a case study with vitamin A (retinol).

30 Aug 2009 The methodology used to establish tolerable upper intake levels (UL) for nutrients borrows heavily from risk assessment methods used by toxicologists. Empirical data are used to identify intake levels associated with adverse effects, and Uncertainty ... Read more...

Latest indexed articles for 'Vitamin A - Metabolism'

These are the very latest articles for this heading:

• Impact of micronutrient deficiencies on obesity. 29 Sep 2009
• N-terminal aliphatic residues dictate the structure, stability, assembly, and small molecule binding of the coiled-coil region of cartilage oligomeric matrix protein. 13 Sep 2009
• Application of a key events dose-response analysis to nutrients: a case study with vitamin A (retinol). 30 Aug 2009
• Metabolism and regulation of gene expression by 4-oxoretinol versus all-trans retinoic acid in normal human mammary epithelial cells. 30 Aug 2009
• Evolutionary changes to transthyretin: structure-function relationships. 27 Aug 2009
• An essential set of basic DNA response elements is required for receptor-dependent transcription of the lecithin:retinol acyltransferase (Lrat) gene. 6 Aug 2009
• A minute dose of 14C-{beta}-carotene is absorbed and converted to retinoids in humans. 15 Jun 2009
• Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearance. Jun 2009
• Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease. 26 May 2009
• Identifying anatomical sites of carotenoid metabolism in birds. 18 May 2009
• [Rate of free radical peroxidation of lipids, activity of adenylate cyclase and permeability of plasma membrane for Ca2+ ions in cells of peripheral blood of sheep exposed to low-level radiation] 29 Apr 2009
• Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic pathways. 25 Apr 2009
• Purified RPE65 shows isomerohydrolase activity after reassociation with a phospholipid membrane. 18 Apr 2009
• Golden Rice is an effective source of vitamin A. 13 Apr 2009
• Vitamin A/retinoids signalling in the human lung. 3 Apr 2009
• Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study. 30 Mar 2009
• Involvement of all-trans-retinal in acute light-induced retinopathy of mice. 18 Mar 2009
• Formation of vitamin A lipid droplets in pancreatic stellate cells requires albumin. 14 Mar 2009
• Antioxidant vitamin status during pregnancy in relation to cognitive development in the first two years of life. 12 Mar 2009
• RBP-to-retinol ratio, but not total RBP, is elevated in patients with type 2 diabetes. 27 Feb 2009

See a longer list of these articles.

Technical information about 'Vitamin A'

Definition: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.

Chemical name: Vitamin A

Registry Number: 11103-57-4

Descriptor UI: D014801

Alternative terms: Vitamin A; Aquasol A; Retinol; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer; All-Trans-Retinol; All Trans Retinol; Vitamin A1; 11-cis-Retinol;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Vitamins;

Tree Number: D02.455.326.271.665.202.495.818; D02.455.426.392.368.367.379.249.700.860; D02.455.849.131.495.818; D23.767.261.700.860;

Online Note: use VITAMIN A to search RETINOL 1969-76

History Note: RETINOL was see under VITAMIN A 1971-76, was see VITAMIN A 1969-70

Technical Notes: /ther use: coordinate disease with /drug ther, not /diet ther