Zinc
Research News and Information

Sunday, November 22, 2009

Characterization and structure of the manganese-responsive transcriptional regulator ScaR.

Nov 2009 The streptococcal coaggregation regulator (ScaR) of Streptococcus gordonii is a manganese-dependent transcriptional regulator. When intracellular manganese concentrations become elevated, ScaR represses transcription of the scaCBA operon, which ... Read more...

Zinc: the brain's dark horse.

30 Oct 2009 Zinc is a life-sustaining trace element, serving structural, catalytic, and regulatory roles in cellular biology. It is required for normal mammalian brain development and physiology, such that deficiency or excess of zinc has been shown to ... Read more...

Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage.

21 Oct 2009 The plasminogen/plasmin system is involved in a variety of normal physiological and pathological processes, including tissue remodelling, angiogenesis and tumour metastasis. Plasminogen activators and receptors for plasminogen/plasminogen activators ... Read more...

Latest indexed articles for 'Zinc'

These are the very latest articles for this heading:

• Characterization and structure of the manganese-responsive transcriptional regulator ScaR. Nov 2009
• Zinc: the brain's dark horse. 30 Oct 2009
• Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage. 21 Oct 2009
• Zinc in the physiology and pathology of the CNS. 12 Oct 2009
• A subset of the diverse COG0523 family of putative metal chaperones is linked to zinc homeostasis in all kingdoms of life. 10 Oct 2009
• Impact of micronutrient deficiencies on obesity. 29 Sep 2009
• Deoxyribonuclease I is essential for DNA fragmentation induced by gamma radiation in mice. 29 Sep 2009
• Soil factors associated with zinc deficiency in crops and humans. 29 Sep 2009
• Immobilising of Cd, Pb, and Zn contaminated arable soils close to a former Pb/Zn smelter: a field study in Austria over 5 years. 29 Sep 2009
• Role of dietary zinc in heat-stressed poultry: a review. 29 Sep 2009
• Effects of feeding different forms of zinc and copper on the performance and tissue mineral content of chicks. 29 Sep 2009
• Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. 29 Sep 2009
• Bioassays for evaluating the water-extractable genotoxic and toxic potential of soils polluted by metal smelters. 29 Sep 2009
• Antenatal and postnatal iron supplementation and childhood mortality in rural Nepal: a prospective follow-up in a randomized, controlled community trial. 22 Sep 2009
• Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3. 22 Sep 2009
• The ALS-associated mutation G93A in human copper-zinc superoxide dismutase selectively destabilizes the remote metal binding region. 20 Sep 2009
• Toxicity of acid mine pit lake water remediated with limestone and phosphorus. 17 Sep 2009
• Zinc-independent folate biosynthesis: genetic, biochemical, and structural investigations reveal new metal dependence for GTP cyclohydrolase IB. 16 Sep 2009
• Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V. 14 Sep 2009
• Separating and recycling metals from mixed metallic particles of crushed electronic wastes by vacuum metallurgy. 13 Sep 2009

See a longer list of these articles.

Technical information about 'Zinc'

Definition: A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.

Registry Number: 7440-66-6

Descriptor UI: D015032

Alternative terms: Zinc;

Related Mesh Headings: Zinc Isotopes; Zinc Radioisotopes;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; classification; deficiency; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Trace Elements;

Tree Number: D01.268.556.940; D01.268.956.906; D01.552.544.940;