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Agrin (Latest Articles)
Latest indexed articles for 'Agrin'
Articles 1 to 10 of 200:
Identification and function of agrin expressed in rat brain microvessels.
30 Aug 2009 
Agrin isoforms in the brain microvessels were investigated. Brain microvessels prepared from rat cerebral cortex expressed the short amino terminal (SN) isoform, which contains a transmembrane sequence of SN agrin, and the long amino terminal (LN) ...
rec_pub_19750929-identification-function-agrin-expressed-rat-brain-microvessels.htm
Identification of an agrin mutation that causes congenital myasthenia and affects synapse function.
21 Jul 2009 We report the case of a congenital myasthenic syndrome due to a mutation in AGRN, the gene encoding agrin, an extracellular matrix molecule released by the nerve and critical for formation of the neuromuscular junction. Gene analysis identified a ...
rec_pub_19631309-identification-agrin-mutation-causes-congenital-myasthenia-affects.htm
[Extracellular matrix protein, Pikachurin, is required for photoreceptor ribbon synapse formation]
29 Jun 2009 
rec_pub_19588880-extracellular-matrix-protein-pikachurin-required-photoreceptor-ribbon.htm
15 Jun 2009 In multiple sclerosis (MS), and its animal model experimental autoimmune encephalomyelitis (EAE), dysfunction of the blood-brain barrier (BBB) leads to edema formation within the central nervous system. The molecular mechanisms of edema formation in ...
rec_pub_19533155-loss-astrocyte-polarity-marks-blood-brain-barrier-impairment.htm
30 May 2009 Agrin is a recently identified proteoglycan component of vascular and bile duct basement membranes in the liver. The selective deposition of agrin in hepatocellular carcinoma (HCC) microvessels versus sinusoidal walls prompted us to investigate the ...
rec_pub_19194276-agrin-cd34-immunohistochemistry-discrimination-benign-versus.htm
Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking.
29 May 2009 Postsynaptic receptor localization is crucial for synapse development and function, but the underlying cytoskeletal mechanisms remain elusive. Using Xenopus neuromuscular junctions as a model, we found that actin depolymerizing factor (ADF)/cofilin ...
rec_pub_19483689-regulation-acetylcholine-receptor-clustering-adf-cofilin-directed.htm
Agrin defines polarized distribution of orthogonal arrays of particles in astrocytes.
14 May 2009 Accumulating evidence indicates that agrin, a heparan sulphate proteoglycan of the extracellular matrix, plays a role in the organization and maintenance of the blood-brain barrier. This evidence is based on the differential effects of agrin ...
rec_pub_19449033-agrin-defines-polarized-distribution-orthogonal-arrays-particles.htm
10 May 2009 The CT carbohydrate, Neu5Ac/Neu5Gcalpha2,3[GalNAcbeta1,4]Galbeta1,4GlcNAcbeta-, is specifically expressed at the neuromuscular junction in skeletal myofibers of adult vertebrates. When Galgt2, the glycosyltransferase that creates the synaptic ...
rec_pub_19442736-the-synaptic-ct-carbohydrate-modulates-binding-expression.htm
Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.
14 Apr 2009 Drugs that inhibit Na,K-ATPases, such as digoxin and ouabain, alter cardiac myocyte contractility. We recently demonstrated that agrin, a protein first identified at the vertebrate neuromuscular junction, binds to and regulates the activity of ...
rec_pub_19376779-agrin-regulation-alpha3-sodium-potassium-atpase-activity-modulates.htm
Aberrant development of neuromuscular junctions in glycosylation-defective Large(myd) mice.
3 Apr 2009 Mice deficient in the glycosyltransferase Large are characterized by severe muscle and central nervous system abnormalities. In this study, we show that the formation and maintenance of neuromuscular junctions in Large(myd) mice are greatly ...
rec_pub_19346129-aberrant-development-neuromuscular-junctions-glycosylation-defective.htm
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