Antineoplastic Agents (Latest Articles)

Latest indexed articles for 'Antineoplastic Agents'

Articles 1 to 10 of 200:

Allogeneic hematopoietic cell transplantation (allogeneic HCT) for treatment of pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL).

13 Dec 2009 BACKGROUND: Allogeneic hematopoietic cell transplant (HCT) with best available donor for children with Philadelphia positive (Ph+) acute lymphoblastic leukemia (ALL) has previously been considered standard practice. Since the introduction of ...
rec_pub_19731318-allogeneic-hematopoietic-cell-transplantation-allogeneic-hct.htm

Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.

13 Dec 2009 BACKGROUND: Ispinesib is a highly specific inhibitor of kinesin spindle protein (KSP, HsEg5), a mitotic kinesin required for separation of the spindle poles. Here we report the activity of ispinesib against the in vitro and in vivo panels of the ...
rec_pub_19554570-initial-testing-stage-1-kinesin-spindle-protein-inhibitor-ispinesib.htm

Continuous and intermittent dosing of lonafarnib potentiates the therapeutic efficacy of docetaxel on preclinical human prostate cancer models.

29 Nov 2009 Lonafarnib is a potent, selective farnesyltransferase inhibitor (FTI) undergoing clinical studies for the treatment of solid tumors and hematological malignancies. Preclinically, a number of FTIs, including lonafarnib, interact with taxanes to ...
rec_pub_19530253-continuous-intermittent-dosing-lonafarnib-potentiates-therapeutic.htm

Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel.

29 Nov 2009 It has recently been shown that docetaxel chemotherapy is effective in prolonging life in patients with prostate cancer (PCa). We have investigated potential ways of increasing the effectiveness of chemotherapy in this disease. We have previously ...
rec_pub_19521959-sphingosine-kinase-1-inhibition-sensitizes-hormone-resistant-prostate.htm

A phase II study of Campath-1H in children with relapsed or refractory acute lymphoblastic leukemia: a Children's Oncology Group report.

29 Nov 2009 BACKGROUND: Despite the increasing cure rates for children with acute lymphoblastic leukemia (ALL), patients who relapse continue to have poor prognosis. The Children's Oncology Group (COG) conducted a limited institution Phase II trial of ...
rec_pub_19637330-a-phase-ii-study-campath-1h-children-relapsed-refractory-acute.htm

The beneficial role of gonadotropin releasing hormone agonists on fertility preservation.

29 Nov 2009
rec_pub_19484751-the-beneficial-role-gonadotropin-releasing-hormone-agonists-fertility.htm

Sustained first remission in an adolescent with hepatosplenic T-cell lymphoma treated with T-cell leukemia induction, nucleoside analog-based consolidation, and early hematopoietic stem cell transplant.

29 Nov 2009 Hepatosplenic T-cell lymphoma (HTCL) is a rare malignancy. Prognosis is poor with only a few case reports of long-term survivors. While HTCL universally involves the bone marrow, the condition has been most often treated with multimodal lymphoma ...
rec_pub_19479793-sustained-remission-adolescent-hepatosplenic-t-cell-lymphoma-treated.htm

Monitoring of ototoxicity in young children receiving carboplatin for retinoblastoma.

29 Nov 2009
rec_pub_19479791-monitoring-ototoxicity-young-children-receiving-carboplatin.htm

Restriction of cisplatin induction of acute apoptosis to a subpopulation of cells in a three-dimensional carcinoma culture model.

13 Nov 2009 Cisplatin is a clinically important chemotherapeutical agent used to treat epithelial malignancies. High concentrations (20-100 microM) of cisplatin have been used in numerous studies to induce apoptosis of carcinoma cells grown in monolayer culture ...
rec_pub_19670329-restriction-cisplatin-induction-acute-apoptosis-subpopulation-cells.htm

Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin.

13 Nov 2009 Clear cell carcinoma (CCC) of the ovary is known to be highly resistant to platinum-based chemotherapy. The purpose of our study was to identify a candidate protein that is associated with chemoresistance of CCC and to investigate the specific ...
rec_pub_19598262-enhanced-expression-annexin-a4-clear-cell-carcinoma-ovary-association.htm

Results: [1-10] [11-20] [21-30] [31-40] [41-50] [51-60] [61-70] [71-80] [81-90] [91-100] [101-110] [111-120] [121-130] [131-140] [141-150] [151-160] [161-170] [171-180] [181-190] [191-200]