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Blotting, Western (Latest Articles)
Latest indexed articles for 'Blotting, Western'
Articles 1 to 10 of 200:
29 Nov 2009 
Endometrial cancer is the most common invasive gynecologic malignancy, yet molecular mechanisms and signaling pathways underlying its etiology and pathophysiology remain poorly characterized. We sought to define a functional role for the protein ...
rec_pub_19672862-protein-kinase-c-alpha-dependent-signaling-mediates-endometrial.htm
29 Nov 2009 Our previous study has suggested that the cell cycle-related kinase (CCRK) is a putative candidate oncogene in glioblastoma tumorigenesis. The potential oncogenic role of CCRK and its clinical/prognostic significance, however, in ovarian carcinoma ...
rec_pub_19672860-cell-cycle-related-kinase-supports-ovarian-carcinoma-cell.htm
RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells.
29 Nov 2009 RhoB, a tumor suppressor, has emerged as an interesting cancer target, and extensive studies aimed at understanding its role in apoptosis have been performed. In our study, we investigated the involvement of RhoB-interacting molecules in apoptosis. ...
rec_pub_19637314-rhob-induces-apoptosis-direct-interaction-tnfaip1-hela-cells.htm
29 Nov 2009 Overexpression of cyclooxygenase-2 (COX-2) and elevation of its derivative prostaglandin E(2) (PGE(2)) are implicated in human esophageal squamous cell carcinoma. The expression of c-Myc, an oncogenic transcription factor, is also upregulated in ...
rec_pub_19623651-prostaglandin-e-2-promotes-cell-proliferation-protein-kinase-c.htm
29 Nov 2009 The tumor suppressor role of annexin-A7 (ANXA7) was previously demonstrated by cancer susceptibility in Anxa7(+/-)-mice and by ANXA7 loss in human cancers, especially in hormone-resistant prostate tumors. To gain mechanistic insights into ANXA7 ...
rec_pub_19610065-annexin-a7-protects-normal-prostate-cells-induces-distinct-patterns.htm
29 Nov 2009 p21-Activated kinase 1 (Pak1), a serine/threonine kinase, has been implicated in cytoskeletal remodelling, cell motility, apoptosis and transformation. However, the role of Pak1 in gastric cancer remains unclear. In this study, we detected Pak1 ...
rec_pub_19610058-downregulation-p21-activated-kinase-1-inhibits-growth-gastric-cancer.htm
29 Nov 2009 Id-1 (inhibitor of differentiation or DNA binding) is a helix-loop-helix protein that is overexpressed in many types of cancer including esophageal squamous cell carcinoma (ESCC). We previously reported that ectopic Id-1 expression activates the ...
rec_pub_19551863-id-1-promotes-tumorigenicity-metastasis-human-esophageal-cancer-cells.htm
Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs.
29 Nov 2009 Metastasis continues to be the leading cause of mortality for patients with cancer. Several years ago, it became clear that chemokines and their receptors could control the tumor progress. CXCR3 has now been identified in many cancers including ...
rec_pub_19544560-antagonism-chemokine-receptor-cxcr3-inhibits-osteosarcoma-metastasis.htm
29 Nov 2009 Apc-deficient Min mice feature low expression of lipoprotein lipase (LPL), high concentration of serum triglyceride (TG), fatty change of the liver and large numbers of intestinal polyps. We have reported that induction of LPL expression reduces ...
rec_pub_19544529-overexpression-low-density-lipoprotein-receptor-lipid-accumulation.htm
29 Nov 2009 Lonafarnib is a potent, selective farnesyltransferase inhibitor (FTI) undergoing clinical studies for the treatment of solid tumors and hematological malignancies. Preclinically, a number of FTIs, including lonafarnib, interact with taxanes to ...
rec_pub_19530253-continuous-intermittent-dosing-lonafarnib-potentiates-therapeutic.htm
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