Decision Making - Drug effects (Latest Articles)

Latest indexed articles for 'Decision Making - Drug effects'

Articles 1 to 10 of 200:

A neurocomputational model for cocaine addiction.

29 Sep 2009 Based on the dopamine hypotheses of cocaine addiction and the assumption of decrement of brain reward system sensitivity after long-term drug exposure, we propose a computational model for cocaine addiction. Utilizing average reward temporal ...
rec_pub_19635010-a-neurocomputational-model-cocaine-addiction.htm

Functional significance of nonspatial information in monkey lateral intraparietal area.

22 Jun 2009 Although the parietal cortex is traditionally associated with spatial perception and motor planning, recent evidence shows that neurons in the lateral intraparietal area (LIP) carry both spatial and nonspatial signals. The functional significance of ...
rec_pub_19553456-functional-significance-nonspatial-information-monkey-lateral.htm

Impairment of cognitive abilities and decision making after chronic use of alcohol: the impact of multiple detoxifications.

30 May 2009 AIMS: In the present study, the effect of previous detoxifications on prefrontal function and decision making was examined in alcohol-dependent patients. Further, we examined whether the length of abstinence affects cognitive function. METHODS: ...
rec_pub_19487491-impairment-cognitive-abilities-decision-making-chronic-use-alcohol.htm

Balancing risk and reward: a rat model of risky decision making.

11 May 2009 We developed a behavioral task in rats to assess the influence of risk of punishment on decision making. Male Long-Evans rats were given choices between pressing a lever to obtain a small, 'safe' food reward and a large food reward associated with ...
rec_pub_19440192-balancing-risk-reward-rat-model-risky-decision-making.htm

On the role of dopamine replacement therapy in decision-making, working memory, and reward in Parkinson's disease: does the therapy-dose matter?

10 May 2009 BACKGROUND: Dopaminergic therapy proved to ameliorate motor deficits in Parkinson's disease but its effects on behavior and cognition vary according to factors that include, among others, the evolution of the disease and the nature of the task that ...
rec_pub_19442427-on-role-dopamine-replacement-therapy-decision-making-working-memory.htm

Perturbations in different forms of cost/benefit decision making induced by repeated amphetamine exposure.

12 Apr 2009 RATIONALE: Psychostimulant abuse has been linked to impairments in cost-benefit decision making. OBJECTIVE: We assessed the effects of repeated amphetamine (AMPH) treatment in rodents on two distinct forms of decision making. MATERIALS AND METHODS: ...
rec_pub_19365622-perturbations-different-forms-cost-benefit-decision-making-induced.htm

Decision-making in long-term cocaine users: Effects of a cash monetary contingency on Gambling task performance.

3 Apr 2009 BACKGROUND: The Iowa Gambling task, which typically incorporates hypothetical monetary earnings and losses for performance, has been widely used to measure decision-making in substance abusers. We examined the effects of a cash monetary contingency ...
rec_pub_19346083-decision-making-long-term-cocaine-users-effects-cash-monetary.htm

Comparing the role of the anterior cingulate cortex and 6-hydroxydopamine nucleus accumbens lesions on operant effort-based decision making.

30 Mar 2009 Both the anterior cingulate cortex (ACC) and mesolimbic dopamine, particularly in the nucleus accumbens (NAc), have been implicated in allowing an animal to overcome effort constraints to obtain greater benefits. However, their exact contribution to ...
rec_pub_19385990-comparing-role-anterior-cingulate-cortex-6-hydroxydopamine-nucleus.htm

Dopamine modulates effort-based decision making in rats.

30 Mar 2009 Previous research has implicated dopamine as a modulating factor in choice behavior based on effort. The purpose of the present study was to determine the individual contribution of different dopamine receptors to effort-based decision making in ...
rec_pub_19331447-dopamine-modulates-effort-based-decision-making-rats.htm

Optimality and robustness of a biophysical decision-making model under norepinephrine modulation.

30 Mar 2009 The locus ceruleus (LC) can exhibit tonic or phasic activity and release norepinephrine (NE) throughout the cortex, modulating cellular excitability and synaptic efficacy and thus influencing behavioral performance. We study the effects of LC-NE ...
rec_pub_19339624-optimality-robustness-biophysical-decision-making-model.htm

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