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Diabetes Mellitus, Type 1 (Latest Articles)
Latest indexed articles for 'Diabetes Mellitus, Type 1'
Articles 1 to 10 of 200:
Images in clinical medicine. Injection-site lipoatrophy.
3 Nov 2009 
rec_pub_19890122-images-clinical-medicine-injection-site-lipoatrophy.htm
Prediction of proliferative diabetic retinopathy with hemoglobin level.
30 Oct 2009 
OBJECTIVE: To investigate the role of hemoglobin (HGB) level in predicting proliferative diabetic retinopathy (PDR). METHODS: We assessed 426 individuals without PDR at baseline (213 men; 213 women) from the Pittsburgh Epidemiology of Diabetes ...
rec_pub_19901215-prediction-proliferative-diabetic-retinopathy-hemoglobin-level.htm
Dry eye reversal and corneal sensation restoration with topical naltrexone in diabetes mellitus.
30 Oct 2009 OBJECTIVE: To determine if topical application of naltrexone hydrochloride (NTX), an opioid antagonist, restores tear production and corneal sensation in rats with diabetes mellitus. METHODS: Type 1 diabetes was induced with streptozotocin in rats. ...
rec_pub_19901212-dry-eye-reversal-corneal-sensation-restoration-topical-naltrexone.htm
30 Oct 2009 Insulin is a critical autoantigen for the development of autoimmune diabetes in non-obese diabetic (NOD) mice. About 80% of NOD females and 30-40% of NOD males develop diabetes. However, Insulin2 (Ins2) knockout NOD mice develop autoimmune diabetes ...
rec_pub_19874548-insulin2-gene-ins2-transcription-nod-bone-marrow-derived-cells-does.htm
Is antigen specificity of autoreactive T cells the key to islet entry?
14 Oct 2009 It has been widely hypothesized that pancreatic islet infiltrates include both islet-antigen-specific and nonspecific T cells. In this issue of Immunity, Lennon et al. (2009) demonstrate that islet-antigen specificity is required for accumulation in ...
rec_pub_19833083-is-antigen-specificity-autoreactive-t-cells-key-islet-entry.htm
13 Oct 2009 Autoimmune diseases develop in selected normal mouse strains when thymectomy (Tx) is performed at 3 days of age (d3-Tx). Insufficient T cell regulation after Tx may result from a defect in regulatory T (Treg) cells or from an augmented effector T ...
rec_pub_19801516-autoimmunity-thymectomy-induced-lymphopenia-role-thymus-ablation.htm
Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion.
13 Oct 2009 The definitions of tolerogenic vs immunogenic dendritic cells (DC) remain controversial. Immature DC have been shown to induce T regulatory cells (Treg) specific for foreign and allogeneic Ags. However, we have previously reported that mature DC ...
rec_pub_19801514-dominant-role-antigen-dose-cd4-foxp3-regulatory-t-cell-induction.htm
Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.
10 Oct 2009 Type I diabetes mellitus is caused by autoimmune destruction of pancreatic beta cells, and effective treatment of the disease might require rescuing beta cell function in a context of reinstalled immune tolerance. Sertoli cells (SCs) are found in ...
rec_pub_19822646-therapy-experimental-type-1-diabetes-isolated-sertoli-cell-xenografts.htm
7 Oct 2009 Insulin deficiency in type 1 diabetes leads to disruptions in glucose, lipid, and ketone metabolism with resultant hyperglycemia, hyperlipidemia, and ketonemia. Exogenous insulin and hepatic insulin gene therapy cannot mimic the robust ...
rec_pub_19819964-gene-therapy-neurogenin-3-betacellulin-reverses-major-metabolic.htm
T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event.
6 Oct 2009 Type 1 diabetes is a T cell-mediated autoimmune disease, characterized by lymphocytic infiltration of the pancreatic islets. It is currently thought that islet antigen specificity is not a requirement for islet entry and that diabetogenic T cells ...
rec_pub_19818656-t-cell-islet-accumulation-type-1-diabetes-tightly-regulated-cell.htm
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