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DNA Primers (Latest Articles)

 

Latest indexed articles for 'DNA Primers'

Articles 1 to 10 of 200:

Kinetic studies of HPr, HPr(H15D), HPr(H15E), and HPr(His approximately P) phosphorylation by the Streptococcus salivarius HPr(Ser) kinase/phosphorylase.

15 Nov 2009 HPr is a central protein of the phosphoenolpyruvate:sugar phosphotransferase transport system (PTS). In streptococci, HPr can be phosphorylated at His(15) at the expense of PEP by enzyme I (EI) of the PTS, producing HPr(His approximately P). HPr can ...
rec_pub_19824696-kinetic-studies-hpr-hpr-h15d-hpr-h15e-hpr-approximately-p.htm


Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach.

15 Nov 2009 Protein synthesis is a highly conserved process in all living cells involving several members of the translation factor (TRAFAC) class of P-loop GTPases, which play essential roles during translation. The universally conserved GTPase HflX has ...
rec_pub_19824612-toward-understanding-function-universally-conserved-gtpase-hflx.htm


Direct interaction between anthrax toxin receptor 1 and the actin cytoskeleton.

8 Nov 2009 The protective antigen component of anthrax toxin binds the I domain of the anthrax toxin receptors, ANTXR1 and ANTXR2, in a manner akin to how integrins bind their ligands. The I domains of integrins and ANTXR1 both have high- and low-affinity ...
rec_pub_19817382-direct-interaction-anthrax-toxin-receptor-1-actin-cytoskeleton.htm


Requirement of a unique Ca(2+)-binding loop for folding of Tk-subtilisin from a hyperthermophilic archaeon.

8 Nov 2009 Tk-subtilisin from the hyperthermophiolic archaeon Thermococcus kodakaraensis matures from Pro-Tk-subtilisin upon autoprocessing and degradation of Tk-propeptide [Tanaka, S., Saito, K., Chon, H., Matsumura, H., Koga, Y., Takano, K., and Kanaya, S. ...
rec_pub_19813760-requirement-unique-ca-2-binding-loop-folding-tk-subtilisin.htm


The SufBCD Fe-S scaffold complex interacts with SufA for Fe-S cluster transfer.

8 Nov 2009 Iron-sulfur clusters are key iron cofactors in biological pathways ranging from nitrogen fixation to respiration. Because of the toxicity of ferrous iron and sulfide to the cell, in vivo Fe-S cluster assembly transpires via multiprotein biosynthetic ...
rec_pub_19810706-the-sufbcd-fe-s-scaffold-complex-interacts-sufa-fe-s-cluster-transfer.htm


Herpes simplex virus-1 helicase-primase: roles of each subunit in DNA binding and phosphodiester bond formation.

Nov 2009 The helicase-primase complex from herpes simplex virus-1 contains three subunits, UL5, UL52, and UL8. We generated each of the potential two-subunit complexes, UL5-UL52, UL5-UL8, and UL52-UL8, and used a series of kinetic and photo-cross-linking ...
rec_pub_19788334-herpes-simplex-virus-1-helicase-primase-roles-subunit-dna-binding.htm


Insulin-like growth factor type I receptor gene expression and obesity in esophageal adenocarcinoma.

30 Oct 2009 The objective of this exploratory study was to evaluate the role of the insulin-like growth factor I receptor (IGF-IR) in esophageal adenocarcinoma (EADC). Using quantitative PCR, we studied IGF-IR mRNA expression in 52 well-characterized surgically ...
rec_pub_19582762-insulin-like-growth-factor-type-receptor-gene-expression-obesity.htm


Using cells devoid of RAS proteins as tools for drug discovery.

30 Oct 2009 Mutational activation of RAS proteins occurs in nearly 30% of all human tumors. To date direct pharmacological inhibition of RAS oncoproteins has not been possible. As a consequence, current strategies are focusing on the development of inhibitors ...
rec_pub_19526460-using-cells-devoid-ras-proteins-tools-drug-discovery.htm


Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis.

30 Oct 2009 We have investigated gene expression patterns underlying reversible and irreversible anchorage-independent growth (AIG) phenotypes to identify more sensitive markers of cell transformation for studies directed at interrogating carcinogenesis ...
rec_pub_19526458-cellular-dichotomy-anchorage-independent-growth-responses-bfgf-tpa.htm


The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice.

30 Oct 2009 The Ron receptor tyrosine kinase is overexpressed in approximately half of all human colon cancers. Increased Ron expression positively correlates with tumor progression, and reduction of Ron levels in human colon adenocarcinoma cells reverses their ...
rec_pub_19452510-the-ron-receptor-tyrosine-kinase-required-adenoma-formation-apc-min.htm

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