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DNA Primers (Latest Articles)
Latest indexed articles for 'DNA Primers'
Articles 1 to 10 of 200:
15 Nov 2009
HPr is a central protein of the phosphoenolpyruvate:sugar phosphotransferase transport system (PTS). In streptococci, HPr can be phosphorylated at His(15) at the expense of PEP by enzyme I (EI) of the PTS, producing HPr(His approximately P). HPr can ...
rec_pub_19824696-kinetic-studies-hpr-hpr-h15d-hpr-h15e-hpr-approximately-p.htm
15 Nov 2009
Protein synthesis is a highly conserved process in all living cells involving several members of the translation factor (TRAFAC) class of P-loop GTPases, which play essential roles during translation. The universally conserved GTPase HflX has ...
rec_pub_19824612-toward-understanding-function-universally-conserved-gtpase-hflx.htm
Direct interaction between anthrax toxin receptor 1 and the actin cytoskeleton.
8 Nov 2009
The protective antigen component of anthrax toxin binds the I domain of the anthrax toxin receptors, ANTXR1 and ANTXR2, in a manner akin to how integrins bind their ligands. The I domains of integrins and ANTXR1 both have high- and low-affinity ...
rec_pub_19817382-direct-interaction-anthrax-toxin-receptor-1-actin-cytoskeleton.htm
8 Nov 2009
Tk-subtilisin from the hyperthermophiolic archaeon Thermococcus kodakaraensis matures from Pro-Tk-subtilisin upon autoprocessing and degradation of Tk-propeptide [Tanaka, S., Saito, K., Chon, H., Matsumura, H., Koga, Y., Takano, K., and Kanaya, S. ...
rec_pub_19813760-requirement-unique-ca-2-binding-loop-folding-tk-subtilisin.htm
The SufBCD Fe-S scaffold complex interacts with SufA for Fe-S cluster transfer.
8 Nov 2009
Iron-sulfur clusters are key iron cofactors in biological pathways ranging from nitrogen fixation to respiration. Because of the toxicity of ferrous iron and sulfide to the cell, in vivo Fe-S cluster assembly transpires via multiprotein biosynthetic ...
rec_pub_19810706-the-sufbcd-fe-s-scaffold-complex-interacts-sufa-fe-s-cluster-transfer.htm
Nov 2009
The helicase-primase complex from herpes simplex virus-1 contains three subunits, UL5, UL52, and UL8. We generated each of the potential two-subunit complexes, UL5-UL52, UL5-UL8, and UL52-UL8, and used a series of kinetic and photo-cross-linking ...
rec_pub_19788334-herpes-simplex-virus-1-helicase-primase-roles-subunit-dna-binding.htm
Insulin-like growth factor type I receptor gene expression and obesity in esophageal adenocarcinoma.
30 Oct 2009
The objective of this exploratory study was to evaluate the role of the insulin-like growth factor I receptor (IGF-IR) in esophageal adenocarcinoma (EADC). Using quantitative PCR, we studied IGF-IR mRNA expression in 52 well-characterized surgically ...
rec_pub_19582762-insulin-like-growth-factor-type-receptor-gene-expression-obesity.htm
Using cells devoid of RAS proteins as tools for drug discovery.
30 Oct 2009
Mutational activation of RAS proteins occurs in nearly 30% of all human tumors. To date direct pharmacological inhibition of RAS oncoproteins has not been possible. As a consequence, current strategies are focusing on the development of inhibitors ...
rec_pub_19526460-using-cells-devoid-ras-proteins-tools-drug-discovery.htm
30 Oct 2009
We have investigated gene expression patterns underlying reversible and irreversible anchorage-independent growth (AIG) phenotypes to identify more sensitive markers of cell transformation for studies directed at interrogating carcinogenesis ...
rec_pub_19526458-cellular-dichotomy-anchorage-independent-growth-responses-bfgf-tpa.htm
The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice.
30 Oct 2009
The Ron receptor tyrosine kinase is overexpressed in approximately half of all human colon cancers. Increased Ron expression positively correlates with tumor progression, and reduction of Ron levels in human colon adenocarcinoma cells reverses their ...
rec_pub_19452510-the-ron-receptor-tyrosine-kinase-required-adenoma-formation-apc-min.htm
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