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Dose-Response Relationship, Drug (Latest Articles)
Latest indexed articles for 'Dose-Response Relationship, Drug'
Articles 1 to 10 of 200:
Adrenal function testing in pediatric cancer survivors.
13 Dec 2009 
BACKGROUND: Central adrenal insufficiency is observed after cranial radiation therapy for cancer. Screening at risk patients is recommended, but the best screening strategy is unknown. METHODS: A retrospective review of pediatric cancer survivors ...
rec_pub_19637328-adrenal-function-testing-pediatric-cancer-survivors.htm
The Viracept-EMS case: impact and outlook.
10 Nov 2009 This perspective first considers the potential impact of the Viracept-EMS case in the framework of the current understanding of the low-dose effects of DNA-reactive chemicals and the approaches used to estimate health risks from genotoxins occurring ...
rec_pub_19866516-the-viracept-ems-case-impact-outlook.htm
30 Oct 2009 OBJECTIVES: The purpose of this study was to evaluate the safety and efficacy of raltegravir vs efavirenz-based antiretroviral therapy after 96 weeks in treatment-naive patients with HIV-1 infection. METHODS: Multicenter, double-blind, randomized ...
rec_pub_19648823-sustained-antiretroviral-effect-raltegravir-96-weeks-combination.htm
30 Oct 2009 OBJECTIVES: To evaluate the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive therapy in adults with partial-onset seizures. MATERIAL AND METHODS: Double-blind, placebo-controlled, parallel-group, multicenter study consisting of an ...
rec_pub_19832771-efficacy-safety-800-1200-mg-eslicarbazepine-acetate-adjunctive.htm
30 Oct 2009 Tonabersat is a novel benzopyran derivative that blocks the cortical spreading depression proposed to be associated with migraine attacks. The ability of single oral doses of 15, 25, 40 and 80 mg of tonabersat to relieve the symptoms of moderate to ...
rec_pub_19723122-tonabersat-gap-junction-modulator-efficacy-safety-two-randomized.htm
"Above all, do no harm": hippocrates.
30 Oct 2009 
rec_pub_19786859-above-harm-hippocrates.htm
30 Oct 2009 BACKGROUND: The current study was designed to test the hypothesis that dexmedetomidine added to ropivacaine would increase the duration of antinociception to a thermal stimulus in a dose-dependent fashion in a rat model of sciatic nerve blockade. ...
rec_pub_19858875-perineural-dexmedetomidine-added-ropivacaine-causes-dose-dependent.htm
Perinatal akathisia: implications for pharmacokinetic changes during pregnancy.
30 Oct 2009
rec_pub_19884238-perinatal-akathisia-implications-pharmacokinetic-changes-pregnancy.htm
30 Oct 2009 Preclinical investigations utilizing murine experimental auto-immune encephalomyelitis (EAE), as well as clinical observations in patients with multiple sclerosis (MS), may suggest alteration of endogenous opioid systems in MS. In this study we used ...
rec_pub_19855075-endogenous-opioids-regulate-expression-experimental-autoimmune.htm
Adequacy of vitamin D replacement in severe deficiency is dependent on body mass index.
30 Oct 2009 BACKGROUND: Obesity is associated with hypovitaminosis D. Whether body mass index (BMI) determines the replacement dose of vitamin D to achieve sufficiency is unclear. OBJECTIVE: To determine the relationship between BMI and serum 25-OH vitamin D ...
rec_pub_19854337-adequacy-vitamin-d-replacement-severe-deficiency-dependent-body-mass.htm
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