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Hypnotics and Sedatives - Pharmacokinetics (Latest Articles)
Latest indexed articles for 'Hypnotics and Sedatives - Pharmacokinetics'
Articles 1 to 10 of 200:
Low-dose oral midazolam reduces fear and distress during needle procedures in children with cancer.
13 Dec 2009 
BACKGROUND: Children with cancer often mention needle procedures as the most frightening, distressing, and sometimes painful aspect of the disease and treatment. The aim was to investigate whether children experience less fear, distress, and/or pain ...
rec_pub_19688837-low-dose-oral-midazolam-reduces-fear-distress-needle-procedures.htm
When drugs disappear from the patient: elimination of intravenous medication by hemodiafiltration.
30 Oct 2009 Twenty-three hours after heart transplantation, life-threatening acute right heart failure was diagnosed in a patient requiring continuous venovenous hemodiafiltration (CVVHDF). Increasing doses of catecholamines, sedatives, and muscle relaxants ...
rec_pub_19843802-when-drugs-disappear-patient-elimination-intravenous-medication.htm
30 Aug 2009 OBJECTIVE: We study the effect of short half-life hypnotics (zaleplon or zolpidem against placebo) on altitude tolerance in 12 nonacclimated male soldiers (age, 22.1 +/- 0.8 years; height, 177.8 +/- 1.7 cm; weight, 69.8 +/- 1.7 kg). METHODS: ...
rec_pub_19780373-short-half-life-hypnotics-preserve-physical-fitness-altitude.htm
30 Jul 2009 In February 2009 the European Medicines Agency (EMEA) approved agomelatine (Valdoxan), a sleep modulating antidepressant, for the treatment of major depressive disorders in adults. Agomelatine is an agonist of melatonergic MT1 and MT2 receptors and ...
rec_pub_19777735-agomelatine.htm
Sedation after intubation using etomidate and a long-acting neuromuscular blocker.
30 May 2009 BACKGROUND: Etomidate is an imidazole hypnotic which is commonly used by emergency medicine physicians during rapid sequence intubation. Etomidate's duration of action is significantly shorter than that of commonly used long-acting paralytic ...
rec_pub_19458564-sedation-intubation-using-etomidate-long-acting-neuromuscular-blocker.htm
29 Apr 2009 Zolpidem is currently the global market leader in the hypnotic arena. Recently several novel zolpidem formulations have been launched in the U.S. or are in the preregistration development phase. These comprise an extended-release form, two types of ...
rec_pub_19584967-novel-zolpidem-formulations.htm
Is propofol the perfect hypnotic agent for procedural sedation in neonates?
29 Apr 2009 INTRODUCTION: Following the landmark observations on the relevance of adequate analgesia and sedation in neonates, neonatologists are in search for short acting agents for procedural sedation. Propofol (2,6 di-isopropylphenol) is considered to be a ...
rec_pub_19442072-is-propofol-perfect-hypnotic-agent-procedural-sedation-neonates.htm
Effects of statins on the pharmacokinetics of midazolam in healthy volunteers.
29 Apr 2009 Lipid-lowering agents, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), are widely used to prevent coronary artery disease and often coadministered with other drugs, but there is a possibility that they induce pharmacological ...
rec_pub_19398603-effects-statins-pharmacokinetics-midazolam-healthy-volunteers.htm
Mixed-effects modeling of the influence of midazolam on propofol pharmacokinetics.
29 Apr 2009 BACKGROUND: The combined administration of anesthetics has been associated with pharmacokinetic interactions that induce concentration changes of up to 30%. Midazolam is often used as a preoperative sedative in advance of a propofol-based ...
rec_pub_19372331-mixed-effects-modeling-influence-midazolam-propofol-pharmacokinetics.htm
30 Mar 2009 REASONS FOR PERFORMING STUDY: Detomidine is commonly used i.v. for sedation and analgesia in horses, but the pharmacokinetics and metabolism of this drug have not been well described. OBJECTIVES: To describe the pharmacokinetics of detomidine and ...
rec_pub_19562897-pharmacokinetics-detomidine-metabolites-following-intravenous.htm
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