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Mass Spectrometry (Latest Articles)
Latest indexed articles for 'Mass Spectrometry'
Articles 1 to 10 of 200:
15 Nov 2009 
While covalent catalytic intermediates of retaining alpha-transglycosylases have been structurally characterized previously, no such information for a hydrolytic alpha-amylase has been obtained. This study presents a new "in situ" enzymatic ...
rec_pub_19803533-directed-situ-inhibitor-elongation-strategy-structurally-characterize.htm
15 Nov 2009 Achieving stabilization of telomeric DNA in G-quadruplex conformation by various organic compounds has been an important goal for the medicinal chemists seeking to develop new anticancer agents. Several compounds are known to stabilize ...
rec_pub_19731964-synthesis-evaluation-novel-class-g-quadruplex-stabilizing-small.htm
30 Oct 2009 Reelin is a secreted glycoprotein that plays pivotal roles in the development and function of the brain, but how it activates downstream intracellular signaling is not fully understood. We have recently reported that the highly conserved C-terminal ...
rec_pub_19530167-c-terminal-region-dependent-change-antibody-binding-eighth-reelin.htm
30 Oct 2009 This work was undertaken to gain further information on the chemical characteristics of the membrane entity involved in the formation of the nonspecific pore. Mitochondria were subjected to oxidative stress by exposure to UV radiation. The results ...
rec_pub_19883225-cyclosporin-inhibits-uv-radiation-induced-membrane-damage-unable.htm
The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.
30 Oct 2009 MAX dimerization protein 1 (MAD1) is a transcription suppressor that antagonizes MYC-mediated transcription activation, and the inhibition mechanism occurs mainly through the competition of target genes' promoter MYC binding sites by MAD1. The ...
rec_pub_19526459-the-suppression-mad1-akt-mediated-phosphorylation-activates-mad1.htm
Molds and mycotoxins in indoor environments--a survey in water-damaged buildings.
30 Oct 2009 Mycotoxins are toxic, secondary metabolites frequently produced by molds in water-damaged indoor environments. We studied the prevalence of selected, potent mycotoxins and levels of fungal biomass in samples collected from water-damaged indoor ...
rec_pub_19757292-molds-mycotoxins-indoor-environments-survey-water-damaged-buildings.htm
Branch-specific sialylation of IgG-Fc glycans by ST6Gal-I.
18 Oct 2009 Sialylated forms of the Fc fragment of immunoglobulin G, produced by the human alpha2-6 sialyltransferase ST6Gal-I, were identified as potent anti-inflammatory mediators in a mouse model of rheumatoid arthritis and are potentially the active ...
rec_pub_19772356-branch-specific-sialylation-igg-fc-glycans-st6gal-i.htm
18 Oct 2009 Oxidative damage to 5-methylcytosine in DNA, followed by deamination, yields thymine glycol (Tg), 5,6-dihydroxy-5,6-dihydrothymine, mispaired with deoxyguanosine. The structure of the 5R Tg.G mismatch pair has been refined using a combination of ...
rec_pub_19772348-the-cis-5r-6s-thymine-glycol-lesion-occupies-wobble-position.htm
Copper binding to beta-2-microglobulin and its pre-amyloid oligomers.
18 Oct 2009 Beta-2-microglobulin (beta2m) deposits as amyloid fibrils in the musculoskeletal system of patients undergoing long-term dialysis treatment as a result of kidney failure. Previous work has shown that Cu(II) binding causes beta2m to organize into ...
rec_pub_19754160-copper-binding-beta-2-microglobulin-pre-amyloid-oligomers.htm
18 Oct 2009 Laforin and starch excess 4 (SEX4) are founding members of a class of phosphatases that dephosphorylate phosphoglucans. Each protein contains a carbohydrate binding module (CBM) and a dual-specificity phosphatase (DSP) domain. The gene encoding ...
rec_pub_19754155-structural-insights-glucan-phosphatase-dynamics-using-amide-hydrogen.htm
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