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Molecular Sequence Data (Latest Articles)

 

Latest indexed articles for 'Molecular Sequence Data'

Articles 1 to 10 of 200:

The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp.

21 Dec 2009 BACKGROUND: The JAL antigen (Rh48) was discovered more than 30 years ago when it caused hemolytic disease of the fetus and newborn in an African American family. A decade later it was found to cause hemolytic disease of the fetus and newborn in a ...
rec_pub_19170983-the-jal-antigen-rh48-result-change-rhce-encodes-arg114trp.htm


Multiply mutated Gaussia luciferases provide prolonged and intense bioluminescence.

25 Nov 2009 Gaussia luciferase (GLuc) from the copepod Gaussia princeps is both the smallest and brightest known luciferase. GLuc catalyzes the oxidation of coelenterazine to produce an intense blue light but with a very short emission half-life. We report ...
rec_pub_19825431-multiply-mutated-gaussia-luciferases-provide-prolonged-intense.htm


Periplasmic domains of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex.

18 Nov 2009 Type IV pili (T4P) are bacterial virulence factors responsible for attachment to surfaces and for twitching motility, a motion that involves a succession of pilus extension and retraction cycles. In the opportunistic pathogen Pseudomonas aeruginosa, ...
rec_pub_19857646-periplasmic-domains-pseudomonas-aeruginosa-piln-pilo-form-stable.htm


The second Cu(II)-binding site in a proton-rich environment interferes with the aggregation of amyloid-beta(1-40) into amyloid fibrils.

15 Nov 2009 The overall morphology and Cu(II) ion coordination for the aggregated amyloid-beta(1-40) [Abeta(1-40)] in N-ethylmorpholine (NEM) buffer are affected by Cu(II) ion concentration. This effect is investigated by transmission electron microscopy (TEM), ...
rec_pub_19824649-the-second-cu-ii-binding-site-proton-rich-environment-interferes.htm


Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase.

15 Nov 2009 While covalent catalytic intermediates of retaining alpha-transglycosylases have been structurally characterized previously, no such information for a hydrolytic alpha-amylase has been obtained. This study presents a new "in situ" enzymatic ...
rec_pub_19803533-directed-situ-inhibitor-elongation-strategy-structurally-characterize.htm


Long-lasting measles outbreak affecting several unrelated networks of unvaccinated persons.

13 Nov 2009 Despite a population immunity level estimated at approximately 95%, an outbreak of measles responsible for 94 cases occurred in Quebec, Canada. Unlike previous outbreaks in which most unvaccinated children belonged to a single community, this ...
rec_pub_19827945-long-lasting-measles-outbreak-affecting-unrelated-networks.htm


Structure of chemokine-derived antimicrobial Peptide interleukin-8alpha and interaction with detergent micelles and oriented lipid bilayers.

8 Nov 2009 Interleukin-8alpha (IL-8alpha) is an antimicrobial peptide derived from the chemokine IL-8. Solution NMR was used to determine the atomic-resolution structure of IL-8alpha in SDS micelles. Solid-state NMR and tryptophan fluorescence were used to ...
rec_pub_19813761-structure-chemokine-derived-antimicrobial-peptide-interleukin-8alpha.htm


Structural basis for the lack of E2 interaction in the RING domain of TRAF2.

8 Nov 2009 TRAF proteins are intracellular signal transducers for a number of immune receptor superfamilies. Specifically, TRAF2 interacts with members of the TNF receptor superfamily and connects the receptors to downstream signaling proteins. It has been ...
rec_pub_19810754-structural-basis-lack-e2-interaction-ring-domain-traf2.htm


Sortase activity is controlled by a flexible lid in the pilus biogenesis mechanism of gram-positive pathogens.

8 Nov 2009 Pili are surface-linked virulence factors that play key roles in infection establishment in a variety of pathogenic species. In Gram-positive pathogens, pilus formation requires the action of sortases, dedicated transpeptidases that covalently ...
rec_pub_19810750-sortase-activity-controlled-flexible-lid-pilus-biogenesis-mechanism.htm


Biologically active sequences in the mouse laminin alpha3 chain G domain.

8 Nov 2009 The laminin alpha3 chain is mainly expressed at the skin, and its C-terminal G domain has a critical role in multiple biological functions. We screened for biologically active sites on the mouse laminin alpha3 chain G domain using 107 synthetic ...
rec_pub_19807150-biologically-active-sequences-mouse-laminin-alpha3-chain-g-domain.htm

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