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Oligonucleotides (Latest Articles)
Latest indexed articles for 'Oligonucleotides'
Articles 1 to 10 of 200:
Development of universal antidotes to control aptamer activity.
2 Oct 2009 
With an ever increasing number of people taking numerous medications, the need to safely administer drugs and limit unintended side effects has never been greater. Antidote control remains the most direct means to counteract acute side effects of ...
rec_pub_19801990-development-universal-antidotes-control-aptamer-activity.htm
29 Sep 2009 We performed a multicentric study to assess the impact of two different culture procedures on the detection of chromosomal abnormalities in 217 consecutive unselected cases with chronic lymphocytic leukemia (CLL) referred for routine analysis either ...
rec_pub_19582829-improved-detection-chromosomal-abnormalities-chronic-lymphocytic.htm
Fluorescence of unmodified oligonucleotides: A tool to probe G-quadruplex DNA structure.
29 Sep 2009 Fluorescence of unmodified oligonucleotides has not been exploited for guanine-quadruplex (G-quadruplex) characterization. We observe that G-rich sequences fluoresce more strongly than duplex or single-stranded DNA but much more weakly than ...
rec_pub_19548317-fluorescence-unmodified-oligonucleotides-tool-probe-g-quadruplex-dna.htm
Quadruple 9-mer-based protein binding microarray with DsRed fusion protein.
16 Sep 2009 BACKGROUND: The interaction between a transcription factor and DNA motif (cis-acting element) is an important regulatory step in gene regulation. Comprehensive genome-wide methods have been developed to characterize protein-DNA interactions. ...
rec_pub_19761621-quadruple-9-mer-based-protein-binding-microarray-dsred-fusion-protein.htm
15 Sep 2009 Agents inducing O(6)-methylguanine (O(6)MeG) in DNA such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) are cytotoxic and a deficiency in mismatch repair (MMR) results in lack of sensitivity to this genotoxin (termed alkylation tolerance). Here, we ...
rec_pub_19766113-mmr-c-abl-dependent-activation-ing2-p73alpha-signaling-regulates-cell.htm
6 Sep 2009 This work describes the rational design, synthesis, and study of a ligand that selectively complexes CUG repeats in RNA (and CTG repeats in DNA) with high nanomolar affinity. This sequence is considered a causative agent of myotonic dystrophy type 1 ...
rec_pub_19805260-a-simple-ligand-selectively-targets-cug-trinucleotide-repeats.htm
6 Sep 2009 Locked nucleic acids (LNA), conformationally restricted nucleotide analogues, are known to enhance pairing stability and selectivity toward complementary strands. With the aim to contribute to a better understanding of the origin of these effects, ...
rec_pub_19670874-comparison-thermodynamics-base-pair-dynamics-full-lna-dna-duplex.htm
30 Aug 2009 
rec_pub_19737023-cu-catalyzed-huisgen-azide-alkyne-1-3-dipolar-cycloaddition-reaction.htm
Sensitive and visual detection of adenosine by a rationally designed FokI-based biosensing strategy.
30 Aug 2009
rec_pub_19591184-sensitive-visual-detection-adenosine-rationally-designed-foki-based.htm
30 Aug 2009
rec_pub_19830904-proceedings-4th-annual-conference-oligonucleotide-therapeutics.htm
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