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Receptor, Serotonin, 5-HT1A (Latest Articles)
Latest indexed articles for 'Receptor, Serotonin, 5-HT1A'
Articles 1 to 10 of 200:
Physical binding pocket induction for affinity prediction.
6 Oct 2009 
Computational methods for predicting ligand affinity where no protein structure is known generally take the form of regression analysis based on molecular features that have only a tangential relationship to a protein/ligand binding event. Such ...
rec_pub_19754201-physical-binding-pocket-induction-affinity-prediction.htm
30 Aug 2009 This study evaluated the 5-HT1A and 5-HT2A receptor positive cells in the cerebella of mice and human by immunocytochemistry. Mice were of ages 1, 3, and 12 months whereas the human subjects were divided into two groups, a younger 57-78 years old ...
rec_pub_19353636-5-ht-1a-2a-receptor-positive-cells-cerebella-mice-human-decline-aging.htm
30 Aug 2009 The medial prefrontal cortex (mPFC) has been proposed to be essential for extinction of fear memory, but its neural mechanism has been poorly understood. The present study examined whether synaptic transmission in the hippocampal-mPFC pathway is ...
rec_pub_19504621-alteration-synaptic-transmission-hippocampal-mpfc-pathway-extinction.htm
29 Aug 2009 Work from our laboratory has previously demonstrated the requirement of membrane cholesterol in the function of the serotonin(1A) receptor, a member of the G-protein coupled receptor (GPCR) superfamily. In order to monitor the effect of cellular ...
rec_pub_19723504-membrane-cholesterol-depletion-live-cells-enhances-function-human.htm
11 Aug 2009 On the basis of the previously reported clinical candidate, SSA-426 (1), a series of related 2-piperazin-1-ylquinoline derivatives 3-16 were synthesized and evaluated as dual-acting serotonin (5-HT) reuptake inhibitors and 5-HT1A receptor ...
rec_pub_19719241-synthesis-potency-vivo-evaluation-2-piperazin-1-ylquinoline-analogues.htm
10 Aug 2009 The modulation of the prefrontal cortex by the neurotransmitter serotonin (5-HT) is thought to play a key role in determining adult anxiety levels. Layer II/III of the prefrontal cortex, which mediates communication across cortical regions, displays ...
rec_pub_19675243-layer-ii-iii-prefrontal-cortex-inhibition-serotonin-5-ht1a-receptor.htm
5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression.
3 Aug 2009 Genes that regulate the serotonin signalling system are potential targets for research in the aetiology of mood disorders and also in the treatment response of serotonin reuptake inhibitors. In this study, we evaluated the association of seven ...
rec_pub_19590397-5-htr1a-5-htr2a-5-htr6-tph1-tph2-polymorphisms-major-depression.htm
30 Jul 2009 OBJECTIVES: To assess effects of a semi-acute administration of buspirone in comparison to a placebo on cognitive function and negative symptoms in patients with schizophrenia and schizoaffective disorder. METHODS: In a 6-week, double-blind, ...
rec_pub_19637398-treatment-cognitive-dysfunction-chronic-schizophrenia-augmentation.htm
Selective serotonin reuptake inhibitor-induced spermatorrhea in 2 patients.
30 Jul 2009 
rec_pub_19758534-selective-serotonin-reuptake-inhibitor-induced-spermatorrhea-2.htm
30 Jul 2009 OBJECTIVES: Various studies indicate that serotonin regulates impulsivity and the inhibitory control of aggression. Aggression is also known to be modified by sex hormones, which exert influence on serotonergic neurotransmission. The present study ...
rec_pub_19086022-aggression-related-frontal-serotonin-1a-receptor-distribution.htm
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