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Receptors, Histamine H1 (Latest Articles)

 

Latest indexed articles for 'Receptors, Histamine H1'

Articles 1 to 10 of 200:

Mast cells down-regulate CD4+CD25+ T regulatory cell suppressor function via histamine H1 receptor interaction.

8 Aug 2009 Mast cells promote both innate and acquired immune responses, but little is known about the effect of mast cells on T regulatory (T(reg)) cell function. In this study, we show for the first time that the capacity of murine CD4(+)CD25(+) T(reg) cells ...
rec_pub_19667094-mast-cells-regulate-cd4-cd25-t-regulatory-cell-suppressor-function.htm


Suplatast tosilate inhibits histamine signaling by direct and indirect down-regulation of histamine H1 receptor gene expression through suppression of histidine decarboxylase and IL-4 gene transcriptions.

11 Jul 2009 Allergic rhinitis (AR) is an inflammatory disorder typified by symptoms such as sneezing, congestion, and rhinorrhea. Histamine plays important roles in eliciting AR symptoms. Up-regulation of the histamine H(1) receptor (H1R) and histidine ...
rec_pub_19596986-suplatast-tosilate-inhibits-histamine-signaling-direct-indirect.htm


Hypothalamic neuronal histamine signaling in the estrogen deficiency-induced obesity.

6 Jul 2009 Menopause is one of the triggers that induce obesity. Estradiol (E2), corticotropin-releasing hormone (CRH), and hypothalamic neuronal histamine are anorexigenic substances within the hypothalamus. This study examined the interactions among E2, CRH, ...
rec_pub_19619143-hypothalamic-neuronal-histamine-signaling-estrogen-deficiency-induced.htm


Differences in the expression of histamine-related genes and proteins in normal human adrenal cortex and adrenocortical tumors.

29 Jun 2009 Histamine is involved in the pathogenesis of several tumors; however, there are no data on its possible involvement in human adrenocortical tumorigenesis. The expression of genes and proteins involved in the biosynthesis (histidine decarboxylase, ...
rec_pub_19568768-differences-expression-histamine-related-genes-proteins-normal-human.htm


Histamine H1 receptor induces cytosolic calcium increase and aquaporin translocation in human salivary gland cells.

12 May 2009 One of the common side effects of antihistamine medicines is xerostomia (dry mouth). The current consensus is that antihistamine-induced xerostomia comes from an antimuscarinic effect. Although the effect of antihistamines on salivary secretion is ...
rec_pub_19443731-histamine-h1-receptor-induces-cytosolic-calcium-increase-aquaporin.htm


Cerebral histamine H1 receptor binding potential measured with PET under a test dose of olopatadine, an antihistamine, is reduced after repeated administration of olopatadine.

12 May 2009 Some antihistamine drugs that are used for rhinitis and pollinosis have a sedative effect as they enter the brain and block the H(1) receptor, potentially causing serious accidents. Receptor occupancy has been measured with PET under single-dose ...
rec_pub_19443589-cerebral-histamine-h1-receptor-binding-potential-measured-pet-test.htm


Histamine hyperpolarizes human glioblastoma cells by activating the intermediate-conductance Ca2+-activated K+ channel.

4 May 2009 The effects of histamine on the membrane potential and currents of human glioblastoma (GL-15) cells were investigated. In perforated whole cell configuration, short (3 s) applications of histamine (100 microM) hyperpolarized the membrane by ...
rec_pub_19420000-histamine-hyperpolarizes-human-glioblastoma-cells-activating.htm


Efficacy and safety of bilastine 20 mg compared with cetirizine 10 mg and placebo for the symptomatic treatment of seasonal allergic rhinitis: a randomized, double-blind, parallel-group study.

2 May 2009 BACKGROUND: Bilastine is a new non-sedative H(1) receptor antagonist, indicated for the treatment of allergic rhinitis (AR) (seasonal and perennial). OBJECTIVE: To assess and compare the efficacy and safety of bilastine 20 mg vs. cetirizine 10 mg ...
rec_pub_19438584-efficacy-safety-bilastine-20-mg-compared-cetirizine-10-mg-placebo.htm


Synthesis and biological evaluation of novel gamma-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists.

May 2009 Synthesis, biological evaluation and structure-activity relationships for a series of novel gamma-carboline analogues of Dimebon are described. Among the studied compounds, gamma-carbolines 3{8} and 3{14} have been identified as potent small ...
rec_pub_19443217-synthesis-biological-evaluation-novel-gamma-carboline-analogues.htm


Histamine H1 receptor knockout mice exhibit impaired spatial memory in the eight-arm radial maze.

29 Apr 2009 BACKGROUND AND PURPOSE: In the mammalian brain, histaminergic neurotransmission is mediated by the postsynaptic histamine H1 and H2 receptors and the presynaptic H3 autoreceptor, which also acts as a heteroreceptor. The H1 receptor has been ...
rec_pub_19413573-histamine-h1-receptor-knockout-mice-exhibit-impaired-spatial-memory.htm

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