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RNA, Messenger (Latest Articles)
Latest indexed articles for 'RNA, Messenger'
Articles 1 to 10 of 200:
PARP1 expression in pediatric central nervous system tumors.
13 Dec 2009 
BACKGROUND: Despite advances in therapy, outcome in many high-grade pediatric central nervous system (CNS) tumors remains poor. The focus of neuro-oncology research has thus turned towards identifying novel therapeutic targets. Poly(ADP-ribose) ...
rec_pub_19533660-parp1-expression-pediatric-central-nervous-system-tumors.htm
29 Nov 2009 Our previous study has suggested that the cell cycle-related kinase (CCRK) is a putative candidate oncogene in glioblastoma tumorigenesis. The potential oncogenic role of CCRK and its clinical/prognostic significance, however, in ovarian carcinoma ...
rec_pub_19672860-cell-cycle-related-kinase-supports-ovarian-carcinoma-cell.htm
29 Nov 2009 Overexpression of cyclooxygenase-2 (COX-2) and elevation of its derivative prostaglandin E(2) (PGE(2)) are implicated in human esophageal squamous cell carcinoma. The expression of c-Myc, an oncogenic transcription factor, is also upregulated in ...
rec_pub_19623651-prostaglandin-e-2-promotes-cell-proliferation-protein-kinase-c.htm
29 Nov 2009 p21-Activated kinase 1 (Pak1), a serine/threonine kinase, has been implicated in cytoskeletal remodelling, cell motility, apoptosis and transformation. However, the role of Pak1 in gastric cancer remains unclear. In this study, we detected Pak1 ...
rec_pub_19610058-downregulation-p21-activated-kinase-1-inhibits-growth-gastric-cancer.htm
29 Nov 2009 Infection with cagA-positive Helicobacter pylori is associated with gastric carcinoma. The cagA-encoded CagA protein is delivered into gastric epithelial cells and, upon tyrosine phosphorylation at the C-terminal EPIYA segments, binds and ...
rec_pub_19588494-differential-oncogenic-potential-geographically-distinct-helicobacter.htm
29 Nov 2009 Apc-deficient Min mice feature low expression of lipoprotein lipase (LPL), high concentration of serum triglyceride (TG), fatty change of the liver and large numbers of intestinal polyps. We have reported that induction of LPL expression reduces ...
rec_pub_19544529-overexpression-low-density-lipoprotein-receptor-lipid-accumulation.htm
29 Nov 2009 HER3 (ERBB3) is a catalytically inactive pseudokinase of the HER receptor tyrosine kinase family, frequently overexpressed in prostate and other cancers. Aberrant expression and mutations of 2 other members of the family, EGFR and HER2, are key ...
rec_pub_19530240-her3-required-maintenance-neuregulin-dependent-independent-attributes.htm
29 Nov 2009 For patients with brain tumors identification of diagnostic and prognostic markers in easy accessible biological material, such as plasma or cerebrospinal fluid (CSF), would greatly facilitate patient management. MIC-1/GDF15 (growth differentiation ...
rec_pub_19521960-elevated-levels-mic-1-gdf15-cerebrospinal-fluid-patients-associated.htm
Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel.
29 Nov 2009 It has recently been shown that docetaxel chemotherapy is effective in prolonging life in patients with prostate cancer (PCa). We have investigated potential ways of increasing the effectiveness of chemotherapy in this disease. We have previously ...
rec_pub_19521959-sphingosine-kinase-1-inhibition-sensitizes-hormone-resistant-prostate.htm
29 Nov 2009 BACKGROUND: Increased activity of multidrug resistance (MDR) genes has been associated with treatment failure in acute leukemias, although with controversial reports. The objective of the present study was to assess the expression profile of the ...
rec_pub_19672972-mrna-expression-profile-multidrug-resistance-genes-childhood-acute.htm
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