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Sequence Alignment (Latest Articles)
Latest indexed articles for 'Sequence Alignment'
Articles 1 to 10 of 200:
From consensus structure prediction to RNA gene finding.
30 Oct 2009 
Reliable structure prediction is a prerequisite for most types of bioinformatical analysis of RNA. Since the accuracy of structure prediction from single sequences is limited, one often resorts to computing the consensus structure for a set of ...
rec_pub_19833701-from-consensus-structure-prediction-rna-gene-finding.htm
Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence.
30 Oct 2009 It has been recently found that muscle fructose 1,6-bisphosphatase (FBPase) is actively transported into cells' nuclei. Results of an analysis in silico of muscle FBPase structure gave rise to a hypothesis that sequence (203)KKKGK(207) is ...
rec_pub_19626708-muscle-fbpase-targeted-nucleus-203kkkgk207-sequence.htm
30 Oct 2009 A Rho GTPase inactivation domain (RID) has been discovered in the multifunctional, autoprocessing RTX toxin RtxA from Vibrio cholerae. The RID domain causes actin depolymerization and rounding of host cells through inactivation of the small Rho ...
rec_pub_19434753-the-rho-gtpase-inactivation-domain-vibrio-cholerae-martx-toxin.htm
Sense from sequence reads: methods for alignment and assembly.
30 Oct 2009 The most important first step in understanding next-generation sequencing data is the initial alignment or assembly that determines whether an experiment has succeeded and provides a first glimpse into the results. In parallel with the growth of new ...
rec_pub_19844229-sense-sequence-reads-methods-alignment-assembly.htm
Computation for ChIP-seq and RNA-seq studies.
30 Oct 2009 Genome-wide measurements of protein-DNA interactions and transcriptomes are increasingly done by deep DNA sequencing methods (ChIP-seq and RNA-seq). The power and richness of these counting-based measurements comes at the cost of routinely handling ...
rec_pub_19844228-computation-chip-seq-rna-seq-studies.htm
30 Oct 2009 There is a growing gap between the generation of massively parallel sequencing output and the ability to process and analyze the resulting data. New users are left to navigate a bewildering maze of base calling, alignment, assembly and analysis ...
rec_pub_19844227-next-generation-gap.htm
20 Oct 2009 BACKGROUND: The Drosophila melanogaster genome contains 29 serpin genes, 12 as single transcripts and 17 within 6 gene clusters. Many of these serpins have a conserved "hinge" motif characteristic of active proteinase inhibitors. However, a ...
rec_pub_19849829-identification-analysis-serpin-family-genes-homology-synteny-12.htm
17 Oct 2009 BACKGROUND: Alternative splicing (AS) of maturing mRNA can generate structurally and functionally distinct transcripts from the same gene. Recent bioinformatic analyses of available genome databases inferred a positive correlation between intron ...
rec_pub_19840385-large-introns-relation-alternative-splicing-gene-evolution-case-study.htm
14 Oct 2009 Human mitochondrial DNA polymerase (Pol gamma) is the sole replicase in mitochondria. Pol gamma is vulnerable to nonselective antiretroviral drugs and is increasingly associated with mutations found in patients with mitochondriopathies. We ...
rec_pub_19837034-structural-insight-processive-human-mitochondrial-dna-synthesis.htm
Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition.
13 Oct 2009 In bacteria, multiple sigmas direct RNA polymerase to distinct sets of promoters. Housekeeping sigmas direct transcription from thousands of promoters, whereas most alternative sigmas are more selective, recognizing more highly conserved promoter ...
rec_pub_19833768-reduced-capacity-alternative-sigmas-melt-promoters-ensures-stringent.htm
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