Serine Endopeptidases (Latest Articles)

Latest indexed articles for 'Serine Endopeptidases'

Articles 1 to 10 of 200:

C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin.

30 Oct 2009 Reelin is a secreted glycoprotein that plays pivotal roles in the development and function of the brain, but how it activates downstream intracellular signaling is not fully understood. We have recently reported that the highly conserved C-terminal ...
rec_pub_19530167-c-terminal-region-dependent-change-antibody-binding-eighth-reelin.htm

Iron-refractory iron deficiency anemia.

29 Sep 2009 Iron-refractory iron deficiency anemia (IRIDA) is an autosomal recessive disorder characterized by iron deficiency anemia unresponsive to oral iron treatment but partially responsive to parenteral iron therapy. IRIDA has recently been shown to be ...
rec_pub_19786206-iron-refractory-iron-deficiency-anemia.htm

Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases.

29 Sep 2009 HtrA1 is a secreted protein which behaves as a molecular chaperone at low temperatures and as a serine protease at high temperatures. When the placenta escapes the normal growth control mechanisms, which are present during normal pregnancy, it may ...
rec_pub_19688690-expression-pattern-alterations-serine-protease-htra1-normal-human.htm

Expression, purification, and characterization of pro-phenoloxidase-activating serine protease from Spodoptera litura.

29 Sep 2009 One of the important trigger molecules for innate immunity is a serine protease that activates zymogen phenol oxidase (PPO). Central to wound healing response is the activation of phenol oxidase zymogen. Molecular characterization of phenol oxidase ...
rec_pub_19557749-expression-purification-characterization-pro-phenoloxidase-activating.htm

Anomalous immunogenic properties of serine proteases.

29 Sep 2009 It has previously been shown that a approximately 27 kDa serine protease of Schistosoma mansoni larvae, the cercarial elastase (CE), was a poor immunogen in as much as it failed to induce an antibody response. The CE has a critical role in enabling ...
rec_pub_19751273-anomalous-immunogenic-properties-serine-proteases.htm

Crystallographic analysis of bacterial signal peptidase in ternary complex with arylomycin A2 and a beta-sultam inhibitor.

27 Sep 2009 Bacterial type I signal peptidase (SPase I), an essential membrane-bound endopeptidase with a unique Ser/Lys dyad mechanism, is being investigated as a potential novel antibiotic target. We present here binding and inhibition assays along with ...
rec_pub_19655811-crystallographic-analysis-bacterial-signal-peptidase-ternary-complex.htm

Membrane type-1 matrix metalloprotease-independent activation of pro-matrix metalloprotease-2 by proprotein convertases.

21 Sep 2009 Matrix metalloprotease-2 is implicated in many biological processes and degrades extracellular and non-extracellular matrix molecules. Matrix metalloprotease-2 maintains a latent state through a cysteine-zinc ion pairing which, when disrupted, ...
rec_pub_19780834-membrane-type-1-matrix-metalloprotease-independent-activation-pro.htm

A new twist on a classic paradigm: illumination of a genetic switch in Vibrio cholerae phage CTX Phi.

9 Sep 2009
rec_pub_19749052-a-new-twist-classic-paradigm-illumination-genetic-switch-vibrio.htm

Evolutionary biology. How beach life favors blond mice.

9 Sep 2009
rec_pub_19745127-evolutionary-biology-beach-life-favors-blond-mice.htm

A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.

8 Sep 2009 Responses to DNA damage are influenced by cellular metabolism through the continuous production of reactive oxygen species (ROS), of which most are by-products of mitochondrial respiration. ROS have a strong influence on signaling pathways during ...
rec_pub_19747897-a-role-nuclear-translocation-tripeptidyl-peptidase-ii-reactive-oxygen.htm

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