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Twist Transcription Factor - Genetics (Latest Articles)
Latest indexed articles for 'Twist Transcription Factor - Genetics'
Articles 1 to 10 of 128:
WNT/beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries?
30 Aug 2009
Based on characterization of both genomic and expression status of WT1 and CTNNB1 (beta-catenin) in a series of 60 Wilms tumor samples, combined with genome-wide expression profiling of these tumors, normal mature and fetal kidney controls, we show ...
rec_pub_19530245-wnt-beta-catenin-pathway-activation-wilms-tumors-unifying-mechanism.htm
Twist expression promotes migration and invasion in hepatocellular carcinoma.
16 Jul 2009
BACKGROUND: Twist, a transcription factor of the basic helix-loop-helix class, is reported to regulate cancer metastasis. It is known to induce epithelial-mesenchymal transition (EMT). In this study, we evaluated the expression of twist and its ...
rec_pub_19615090-twist-expression-promotes-migration-invasion-hepatocellular-carcinoma.htm
29 Jun 2009
Saethre-Chotzen syndrome (SCS) is a rare autosomal dominant syndrome involving craniosynostosis, craniofacial abnormalities, and syndactyly. A recent Scandinavian study reported an increased risk of breast cancer in individuals with a clinical ...
rec_pub_19373776-breast-cancer-risk-increased-individuals-twist1-mutation-confirmed.htm
Negative regulation of TIMP1 is mediated by transcription factor TWIST1.
29 Jun 2009
TWIST1 is involved in tumor invasion and metastasis by promoting epithelial-to-mesenchymal transition. However, the molecular target of TWIST1 involving this mechanism is poorly understood. To identify the TWIST1-regulated genes, we established the ...
rec_pub_19513566-negative-regulation-timp1-mediated-transcription-factor-twist1.htm
28 Jun 2009
Four members of the twist gene family (twist1a, 1b, 2, and 3) are found in the zebrafish, and they are thought to have arisen through three rounds of gene duplication, two of which occurred prior to the tetrapod-fish split. Phylogenetic analysis ...
rec_pub_19565261-phylogenetic-evolutionary-relationships-developmental-expression.htm
21 Jun 2009
The establishment of metastasis depends on the ability of cancer cells to acquire a migratory phenotype combined with their capacity to recreate a secondary tumor in a distant tissue. In epithelial cancers, such as those of the breast, the ...
rec_pub_19549913-a-novel-lung-metastasis-signature-links-wnt-signaling-cancer-cell.htm
Characterization of sequences in human TWIST required for nuclear localization.
15 Jun 2009
BACKGROUND: Twist is a transcription factor that plays an important role in proliferation and tumorigenesis. Twist is a nuclear protein that regulates a variety of cellular functions controlled by protein-protein interactions and gene transcription ...
rec_pub_19534813-characterization-sequences-human-twist-required-nuclear-localization.htm
Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.
3 Jun 2009
Vitamin D receptor (VDR) mediates the antitumoral action of the active vitamin D metabolite 1alpha,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). VDR expression is lost during colon cancer progression causing unresponsiveness to 1,25(OH)(2)D(3) and its ...
rec_pub_19502595-snail2-cooperates-snail1-repression-vitamin-d-receptor-colon-cancer.htm
Jun 2009
The gene vestigial (vg) plays a key role in indirect flight muscle (IFM) development. We show here that vg is controlled by the Notch anti-myogenic signaling pathway in myoblasts and is regulated by a novel 822 bp enhancer during IFM ...
rec_pub_19500564-integration-differentiation-signals-indirect-flight-muscle-formation.htm
30 May 2009
rec_pub_19483582-discussion-reoperation-intracranial-hypertension-twist1-confirmed.htm
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