Computer Simulation (Latest Articles)

Latest indexed articles for 'Computer Simulation'

Articles 101 to 110 of 200:

Entropic organization of interphase chromosomes.

12 Sep 2009 Chromosomes are not distributed randomly in nuclei. Appropriate positioning can activate (or repress) genes by bringing them closer to active (or inactive) compartments like euchromatin (or heterochromatin), and this is usually assumed to be driven ...
rec_pub_19752020-entropic-organization-interphase-chromosomes.htm

Fragmentation of grid cell maps in a multicompartment environment.

11 Sep 2009 To determine whether entorhinal spatial representations are continuous or fragmented, we recorded neural activity in grid cells while rats ran through a stack of interconnected, zig-zagged compartments of equal shape and orientation (a hairpin ...
rec_pub_19749749-fragmentation-grid-cell-maps-multicompartment-environment.htm

Zipping and unzipping of adenylate kinase: atomistic insights into the ensemble of open<-->closed transitions.

10 Sep 2009 Adenylate kinase (AdK), a phosphotransferase enzyme, plays an important role in cellular energy homeostasis. It undergoes a large conformational change between an open and a closed state, even in the absence of substrate. We investigate the apo-AdK ...
rec_pub_19751742-zipping-unzipping-adenylate-kinase-atomistic-insights-ensemble-open.htm

Extraction of morphometry and branching angles of porcine coronary arterial tree from CT images.

9 Sep 2009 The morphometry (diameters, length, and angles) of coronary arteries is related to their function. A simple, easy, and accurate image-based method to seamlessly extract the morphometry for coronary arteries is of significant value for understanding ...
rec_pub_19749169-extraction-morphometry-branching-angles-porcine-coronary-arterial.htm

Parallel computational subunits in dentate granule cells generate multiple place fields.

9 Sep 2009 A fundamental question in understanding neuronal computations is how dendritic events influence the output of the neuron. Different forms of integration of neighbouring and distributed synaptic inputs, isolated dendritic spikes and local regulation ...
rec_pub_19750211-parallel-computational-subunits-dentate-granule-cells-generate.htm

Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib.

9 Sep 2009 Imatinib mesylate induces complete cytogenetic responses in patients with chronic myeloid leukemia (CML), yet many patients have detectable BCR-ABL transcripts in peripheral blood even after prolonged therapy. Bone marrow studies have shown that ...
rec_pub_19749982-eradication-chronic-myeloid-leukemia-stem-cells-novel-mathematical.htm

Pretraining on Southwestern stations decreases training time and cost for proficiency-based fundamentals of laparoscopic surgery training.

9 Sep 2009 BACKGROUND: We previously reported a proficiency-based Fundamentals of Laparoscopic Surgery (FLS) curriculum that uniformly resulted in passing the technical skills certification criteria. We hypothesized that pretraining using the Southwestern (SW) ...
rec_pub_19854404-pretraining-southwestern-stations-decreases-training-time-cost.htm

Improving power in genetic-association studies via wavelet transformation.

9 Sep 2009 BACKGROUND: A key to increasing the power of multilocus association tests is to reduce the number of degrees of freedom by suppressing noise from data. One of the difficulties is to decide how much noise to suppress. An often overlooked problem is ...
rec_pub_19747393-improving-power-genetic-association-studies-wavelet-transformation.htm

Concentration polarization of high-density lipoprotein and its relation with shear stress in an in vitro model.

8 Sep 2009 The purpose of this study was to determine the concentration polarization of high-density lipoprotein (HDL) at the surface of the carotid artery under conditions of steady flow and to establish its relationship with shear stress using an in vitro ...
rec_pub_19753319-concentration-polarization-high-density-lipoprotein-relation-shear.htm

Predictable irregularities in retinal receptive fields.

8 Sep 2009 Understanding how the nervous system achieves reliable performance using unreliable components is important for many disciplines of science and engineering, in part because it can suggest ways to lower the energetic cost of computing. In vision, ...
rec_pub_19805327-predictable-irregularities-retinal-receptive-fields.htm

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