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Serine Endopeptidases (Latest Articles)
Latest indexed articles for 'Serine Endopeptidases'
Articles 171 to 180 of 200:
28 Apr 2009 
Recent whole genome association studies provided little evidence that polymorphisms at the familial Parkinsonism loci influence the risk for Parkinson's disease (PD). However, these studies are not designed to detect the types of subtle effects that ...
rec_pub_19224617-do-polymorphisms-familial-parkinsonism-genes-contribute-risk-sporadic.htm
27 Apr 2009 Staphylococcus aureus has one essential type I signal peptidase (SPase), SpsB, which has emerged as a potential target in the search for antibiotics with a new mode of action. In this framework, the biochemical properties of SpsB are described and ...
rec_pub_19438721-enzymatic-investigation-staphylococcus-aureus-type-signal-peptidase.htm
26 Apr 2009 OBJECTIVE: Although protein malnutrition impairs immune functions, several studies have recently shown that protein restriction without malnutrition is beneficial to host defenses against invading pathogens and cancer. In an effort to establish the ...
rec_pub_19403266-beneficial-effects-low-protein-diet-host-resistance-paracoccidioides.htm
Boosting antimicrobial peptides by hydrophobic oligopeptide end tags.
25 Apr 2009 A novel approach for boosting antimicrobial peptides through end tagging with hydrophobic oligopeptide stretches is demonstrated. Focusing on two peptides derived from kininogen, GKHKNKGKKNGKHNGWK (GKH17) and HKHGHGHGKHKNKGKKN (HKH17), tagging ...
rec_pub_19398550-boosting-antimicrobial-peptides-hydrophobic-oligopeptide-end-tags.htm
22 Apr 2009 A protease-producing bacterium was isolated from an alkaline wastewater of the soap industry and identified as Vibrio metschnikovii J1 on the basis of the 16S rRNA gene sequencing and biochemical properties. The strain was found to over-produce ...
rec_pub_19390884-molecular-biochemical-characterization-extracellular-serine-protease.htm
Identification of HCV protease inhibitor resistance mutations by selection pressure-based method.
22 Apr 2009 
A major challenge to successful antiviral therapy is the emergence of drug-resistant viruses. Recent studies have developed several automated analyses of HIV sequence polymorphism based on calculations of selection pressure (K(a)/K(s)) to predict ...
rec_pub_19395595-identification-hcv-protease-inhibitor-resistance-mutations-selection.htm
Processing of the phalloidin proprotein by prolyl oligopeptidase from the mushroom Conocybe albipes.
21 Apr 2009 The peptide toxins of poisonous Amanita mushrooms are bicyclic octapeptides (amatoxins) or heptapeptides (phallotoxins). In Amanita bisporigera, alpha-amanitin and phallacidin are synthesized as 35- and 34-amino acid proproteins, respectively, in ...
rec_pub_19389704-processing-phalloidin-proprotein-prolyl-oligopeptidase-mushroom.htm
Matriptase-deficient mice exhibit ichthyotic skin with a selective shift in skin microbiota.
21 Apr 2009 Suppressor of tumorigenicity 14 (St14) encodes matriptase, a serine protease, which regulates processing of profilaggrin to filaggin in vivo. Here, we report that transgenic mice with 1% of wild-type St14 levels (St14(hypo/-)) display aberrant ...
rec_pub_19387477-matriptase-deficient-mice-exhibit-ichthyotic-skin-selective-shift.htm
Alternative proteolytic processing of hepatocyte growth factor during wound repair.
21 Apr 2009 Wound healing is a crucial regenerative process in all organisms. We examined expression, integrity, and function of the proteins in the hepatocyte growth factor (HGF)/c-Met signaling pathway in normally healing and non-healing human skin wounds. ...
rec_pub_19389925-alternative-proteolytic-processing-hepatocyte-growth-factor-wound.htm
21 Apr 2009 Hepatocyte growth factor activator inhibitor-1 (HAI)-1 is an epithelial Kunitz-type transmembrane serine protease inhibitor that is encoded by the SPINT1 gene. HAI-1 displays potent inhibitory activity toward a large number of trypsin-like serine ...
rec_pub_19389929-loss-matriptase-suppression-underlies-spint1-mutation-associated.htm
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