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Computer Simulation (Latest Articles)
Latest indexed articles for 'Computer Simulation'
Articles 21 to 30 of 200:
Discovery of novel types of inhibitors of S-adenosylmethionine synthesis by virtual screening.
6 Oct 2009
S-adenosylmethionine (AdoMet) lies at an intersection of nucleotide and amino acid metabolism and performs a multitude of metabolic functions. AdoMet formation is catalyzed by S-adenosylmethionine synthetase (ATP: L-methionine S-adenosyltransferase ...
rec_pub_19739644-discovery-novel-types-inhibitors-s-adenosylmethionine-synthesis.htm
Properties of piriform cortex pyramidal cell dendrites: implications for olfactory circuit design.
5 Oct 2009
Unlike the neocortex, sensory input to the piriform cortex is anatomically segregated in layer 1, making it ideal for studying the dendritic integration of synaptic inputs pivotal for sensory information processing. Here we investigated dendritic ...
rec_pub_19812339-properties-piriform-cortex-pyramidal-cell-dendrites-implications.htm
Discovery properties of genome-wide association signals from cumulatively combined data sets.
4 Oct 2009
Genetic effects for common variants affecting complex disease risk are subtle. Single genome-wide association (GWA) studies are typically underpowered to detect these effects, and combination of several GWA data sets is needed to enhance discovery. ...
rec_pub_19808636-discovery-properties-genome-wide-association-signals-cumulatively.htm
A computational study of lambda-lac mutants.
4 Oct 2009
We present a comprehensive, computational study of the properties of bacteriophage lambda mutants designed by Atsumi and Little (2006 Proc. Natl. Acad. Sci. 103 4558-63). These phages underwent a genetic reconstruction where Cro was replaced by a ...
rec_pub_19809101-a-computational-study-lambda-lac-mutants.htm
4 Oct 2009
BACKGROUND: Because of previous sleep disturbance and sleep hypoxia, patients with obstructive sleep apnea (OSA) might be more vulnerable to the effects of alcohol and sleep restriction than healthy persons. OBJECTIVE: To compare the effects of ...
rec_pub_19805768-effects-alcohol-sleep-restriction-simulated-driving-performance.htm
4 Oct 2009
rec_pub_19805765-summaries-patients-effects-limited-sleep-alcohol-driving-performance.htm
3 Oct 2009
Understanding how RNA molecules navigate their rugged folding landscapes holds the key to describing their roles in a variety of cellular functions. To dissect RNA folding at the molecular level, we performed simulations of three pseudoknots (MMTV ...
rec_pub_19805055-assembly-mechanisms-rna-pseudoknots-determined-stabilities.htm
29 Sep 2009
The ozone (O3) sensitivity to nitrogen oxides (NOx, or nitric oxide [NO] + nitrogen dioxide [NO2]) versus volatile organic compounds (VOCs) in the Mexico City metropolitan area (MCMA) is a current issue of scientific controversy. To shed light on ...
rec_pub_19842324-assessment-ozone-nitrogen-oxide-volatile-organic-compound-sensitivity.htm
29 Sep 2009
OBJECTIVE: Heterogeneity of patients is a common problem in randomized controlled trials (RCTs) in various fields of clinical research. We aimed to investigate the potential benefits of different approaches for dealing with heterogeneity in a case ...
rec_pub_19885979-baseline-characteristics-statistical-power-randomized-controlled.htm
Operant matching as a Nash equilibrium of an intertemporal game.
29 Sep 2009
Over the past several decades, economists, psychologists, and neuroscientists have conducted experiments in which a subject, human or animal, repeatedly chooses between alternative actions and is rewarded based on choice history. While individual ...
rec_pub_19635021-operant-matching-nash-equilibrium-intertemporal-game.htm
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