Reversal Learning (Latest Articles)

Latest indexed articles for 'Reversal Learning'

Articles 81 to 90 of 200:

Amygdala and orbitofrontal cortex lesions differentially influence choices during object reversal learning.

11 Aug 2008 In nonhuman primates, interaction between the orbitofrontal cortex (OFC) and the amygdala (AMG) has been seen as critical for learning and subsequently changing associations between stimuli and reinforcement. However, it is still unclear what the ...
rec_pub_18701696-amygdala-orbitofrontal-cortex-lesions-differentially-influence.htm

Repeated heroin in rats produces locomotor sensitization and enhances appetitive Pavlovian and instrumental learning involving food reward.

6 Aug 2008 We tested the hypothesis that sensitization to heroin enhances appetitive motivational processes involving food reward. In Experiment 1, sixteen rats were exposed to positive pairings of a light stimulus and food for 4 consecutive daily sessions. ...
rec_pub_18755208-repeated-heroin-rats-produces-locomotor-sensitization-enhances.htm

Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test.

3 Aug 2008 One of the key pro-inflammatory mediators activated by amyloid protein in neurodegenerative disorders of the brain, such as Alzheimer's disease is the complement system. Vaccinia virus complement control protein secreted by vaccinia virus, commonly ...
rec_pub_18679819-intracranial-administration-vaccinia-virus-complement-control-protein.htm

How to accurately detect autobiographical events.

30 Jul 2008 We describe a new method, based on indirect measures of implicit autobiographical memory, that allows evaluation of which of two contrasting autobiographical events (e.g., crimes) is true for a given individual. Participants were requested to ...
rec_pub_18816284-how-accurately-detect-autobiographical-events.htm

An increase in Abeta42 in the prefrontal cortex is associated with a reversal-learning impairment in Alzheimer's disease model Tg2576 APPsw mice.

30 Jul 2008 The medial temporal lobe-dependent memory loss associated with Alzheimer's disease (AD) is often accompanied by a loss of prefrontal cortex-dependent cognitive domains that fall under the broad category of executive function. In this study, we ...
rec_pub_18690835-an-increase-abeta42-prefrontal-cortex-associated-reversal-learning.htm

Orbitofrontal dysfunction in patients with obsessive-compulsive disorder and their unaffected relatives.

16 Jul 2008 Obsessive-compulsive disorder (OCD) is characterized by repetitive thoughts and behaviors associated with underlying dysregulation of frontostriatal circuitry. Central to neurobiological models of OCD is the orbitofrontal cortex, a neural region ...
rec_pub_18635808-orbitofrontal-dysfunction-patients-obsessive-compulsive-disorder.htm

Reinforcement and reversal learning in first-episode psychosis.

13 Jul 2008 BACKGROUND: Abnormalities in reinforcement learning and reversal learning have been reported in psychosis, possibly secondary to subcortical dopamine abnormalities. METHODS: We studied simple discrimination (SD) learning and reversal learning in a ...
rec_pub_18628272-reinforcement-reversal-learning-episode-psychosis.htm

Inhibition of the norepinephrine transporter improves behavioral flexibility in rats and monkeys.

5 Jul 2008 RATIONALE: Poor cognitive control, including reversal learning deficits, has been reported in children with attention deficit hyperactivity disorder, in stimulant-dependent humans, and in animal models of these disorders; these conditions have each ...
rec_pub_18604598-inhibition-norepinephrine-transporter-improves-behavioral-flexibility.htm

A mouse model of fragile X syndrome exhibits heightened arousal and/or emotion following errors or reversal of contingencies.

29 Jun 2008 This study was designed to further assess cognitive and affective functioning in a mouse model of Fragile X syndrome (FXS), the Fmr1(tm1Cgr) or Fmr1 "knockout" (KO) mouse. Male KO mice and wild-type littermate controls were tested on learning set ...
rec_pub_18551464-a-mouse-model-fragile-x-syndrome-exhibits-heightened-arousal-emotion.htm

Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats.

28 Jun 2008 RATIONALE: Chronic stress perturbs modulatory brain neurotransmitter systems, including serotonin (5-HT), and is a risk factor for psychiatric disorders such as depression. Deficits in cognitive flexibility, reflecting prefrontal cortical ...
rec_pub_18587666-chronic-intermittent-cold-stress-serotonin-depletion-induce-deficits.htm

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