Research article summary (published 29 Jun 1999):

Limonoids from fruit of Melia toosendan and their cytotoxic activity.

Full Abstract

Two new limonoids, toosendanal and 12-O-methylvolkensin, were isolated from the fruits of Melia toosendan Sieb. et Zucc. along with three known limonoids, meliatoxin B1, trichillin H, and toosendanin. The structures of the new limonoids were established by spectroscopic methods, with toosendanal having C-1/C-29 and C-19/C-29 acetal bridges. Both meliatoxin B1 and toosendanin exhibit cytotoxic activity against KB cells.

Author information

Author/s: Tada, K (K); Takido, M (M); Kitanaka, S (S);

Affiliation: College of Pharmacy, Nihon University, Chiba, Japan.

Journal and publication information

Publication Type: Journal Article

Journal: Phytochemistry (Phytochemistry), published in UNITED STATES. (Language: eng)

Reference: 1999-Jul; vol 51 (issue 6) : pp 787-91

Dates: Created 1999/07/15; Completed 1999/07/15; Revised 2004/11/17;

PMID: 10389275, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Antineoplastic Agents, Phytogenic - chemistry; isolation & purification; pharmacology Drug Screening Assays, Antitumor Drugs, Chinese Herbal - chemistry; isolation & purification; pharmacology Humans Magnetic Resonance Spectroscopy

Magnetic Resonance Spectroscopy Molecular Structure Plants, Medicinal - chemistry Triterpenes - chemistry; isolation & purification; pharmacology Tumor Cells, Cultured

Associated Chemicals: Antineoplastic Agents, Phytogenic (0) ; Drugs, Chinese Herbal (0) ; Triterpenes (0)

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