Effect of mandibular advancement splint on psycho-intellectual derangements in patients with sleep apnea syndrome.

Full Abstract

The mandibular advancement splint (MAS) was recently introduced for the management of sleep apnea syndrome (SAS), although its effects on psycho-intellectual functions have not been elucidated yet. We examined psycho-intellectual function before and after treatment with MAS in patients with SAS. Twenty patients with SAS underwent psycho-intellectual function testing before and after treatment with MAS for 3 to 4 weeks. The apnea index significantly decreased from 19.0+/-15.6 to 2.4+/-1.9. The state anxiety score significantly decreased from 44.6+/-12.1 to 33.7+/-11.1, the trait anxiety score significantly decreased from 46.2+/-13.4 to 37.6+/-13.8, and the depression scale score significantly decreased from 39.2+/-11.0 to 30.8+/-9.9 with MAS treatment. By the Cornell Medical Index and the Yatabe-Guilford test, the patients became less neurotic and less eccentric after treatment. By the Uchida-Kraepelin psychodiagnostic test, calculation ability significantly increased from 1247.4+/-402.1 to 1950.2+/-651.9. We conclude that MAS treatment reduces apneic episodes and improves psycho-intellectual derangements in patients with SAS.

Author information

Author/s: Nambu, Y (Y); Nagasaka, Y (Y); Fujita, E (E); Hamada, S (S); Fukuoka, M (M);

Affiliation: The Fourth Department of Internal Medicine, Kinki University School of Medicine, Osakasayama, Japan.

Journal and publication information

Publication Type: Journal Article

Journal: The Tohoku journal of experimental medicine (Tohoku J Exp Med), published in JAPAN. (Language: eng)

Reference: 1999-Jun; vol 188 (issue 2) : pp 119-32

Dates: Created 1999/11/12; Completed 1999/11/12; Revised 2004/11/17;

PMID: 10526873, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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