[Congenital manifestations of juvenile xanthogranuloma (large nodular form)]

(Kongenitales Auftreten juveniler Xanthogranulome (grossknotige Form).)

Full Abstract

An infant girl presented at birth with multiple, large nodular xanthogranulomas. Her monozygotic twin sister was not affected. The congenital tumors were up to 1.5 cm in diameter, done-shaped and mainly located on the head and the upper half of the body. Histologically the cells were characterized as CD68+ non-Langerhans histiocytes. Follow-up for 18 months showed no new tumors and regression of the existing ones. No extra-cutaneous manifestations were observed. Knowledge of the differential diagnosis, especially the group of Langerhans cell histiocytosis, is essential for prognosis estimation.

Author information

Author/s: Jung, T (T); Emmert, S (S); Günzl, H J (HJ); Neumann, C (C); Rünger, T M (TM);

Affiliation: Abteilung für Dermatologie und Venerologie, Georg-August-Universität Göttingen.

Journal and publication information

Publication Type: Case Reports; English Abstract; Journal Article

Journal: Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt), published in GERMANY. (Language: ger)

Reference: 2000-Jun; vol 51 (issue 6) : pp 423-6

Dates: Created 2000/09/26; Completed 2000/09/26; Revised 2006/11/15;

PMID: 10907158, status: MEDLINE (last retrieved date: 2/18/2009)

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