Research article summary (published 29 Apr 2001):

Numerous gene rearrangements in the mitochondrial genome of the wallaby louse, Heterodoxus macropus (Phthiraptera).

Full Abstract

The complete arrangement of genes in the mitochondrial (mt) genome is known for 12 species of insects, and part of the gene arrangement in the mt genome is known for over 300 other species of insects. The arrangement of genes in the mt genome is very conserved in insects studied, since all of the protein-coding and rRNA genes and most of the tRNA genes are arranged in the same way. We sequenced the entire mt genome of the wallaby louse, Heterodoxus macropus, which is 14,670 bp long and has the 37 genes typical of animals and some noncoding regions. The largest noncoding region is 73 bp long (93% A+T), and the second largest is 47 bp long (92% A+T). Both of these noncoding regions seem to be able to form stem-loop structures. The arrangement of genes in the mt genome of this louse is unlike that of any other animal studied. All tRNA genes have moved and/or inverted relative to the ancestral gene arrangement of insects, which is present in the fruit fly Drosophila yakuba. At least nine protein-coding genes (atp6, atp8, cox2, cob, nad1-nad3, nad5, and nad6) have moved; moreover, four of these genes (atp6, atp8, nad1, and nad3) have inverted. The large number of gene rearrangements in the mt genome of H. macropus is unprecedented for an arthropod.

Author information

Author/s: Shao, R (R); Campbell, N J (NJ); Barker, S C (SC);

Affiliation: Department of Microbiology and Parasitology, and Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal: Molecular biology and evolution (Mol Biol Evol), published in United States. (Language: eng)

Reference: 2001-May; vol 18 (issue 5) : pp 858-65

Dates: Created 2001/04/25; Completed 2001/07/12; Revised 2006/11/15;

PMID: 11319269, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: 18 Feb 2009 00:00:00)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adenine - chemistry Animals Base Sequence DNA - genetics DNA Primers DNA, Mitochondrial - chemistry; genetics; isolation & purification Gene Order Gene Rearrangement - genetics Genes Insects Lice - genetics

Molecular Sequence Data Nucleic Acid Amplification Techniques Nucleic Acid Conformation Phylogeny Polymerase Chain Reaction RNA - genetics RNA, Ribosomal - genetics RNA, Transfer - genetics Sequence Homology, Nucleic Acid Species Specificity Thymine - chemistry

Associated Chemicals: DNA Primers (0) ; DNA, Mitochondrial (0) ; RNA, Ribosomal (0) ; RNA (63231-63-0) ; Thymine (65-71-4) ; Adenine (73-24-5) ; DNA (9007-49-2) ; RNA, Transfer (9014-25-9)

Related articles

These are the highest related articles currently in the database:

• A different tempo of mitochondrial DNA evolution in birds and their parasitic lice. 30 Mar 1998
• Louse (Insecta: Phthiraptera) mitochondrial 12S rRNA secondary structure is highly variable. 30 Jul 2002
• Complete mtDNA sequences of two millipedes suggest a new model for mitochondrial gene rearrangements: duplication and nonrandom loss. 30 Jan 2002
• Complete mitochondrial genome sequence of the wine yeast Candida zemplinina: intraspecies distribution of a novel group-IIB1 intron with eubacterial affiliations. 11 Dec 2007
• Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences. 30 Oct 1990
• Microuli, a family of miniature subterminal inverted-repeat transposable elements (MSITEs): transposition without terminal inverted repeats. 29 Apr 2001
• Gene rearrangements and evolution of tRNA pseudogenes in the mitochondrial genome of the parrotfish (Teleostei: Perciformes: Scaridae). 30 Aug 2004
• The perils of using host relationships in parasite taxonomy: phylogeny of the Degeeriella complex. 29 Apr 2002
• Thiophene-based diamidine forms a "super" at binding minor groove agent. 25 Oct 2004

See 100+ related articles.

Related Article Map

Legend: - FREE Full text Article. - Abstract only. - Title only. More help.

See a large map of 100+ related articles.