Research article summary (published 30 May 2001):

Source localization of EEG activity during hypnotically induced anxiety and relaxation.

Full Abstract

The engagement of different brain regions which implement subjectively experienced emotional states in normals is not completely clarified. Emotional states can conveniently be induced by hypnosis-based suggestions. We studied brain electric activity during hypnotically induced anxiety and relaxation in 11 right-handed normals (5 males, 6 females, mean age 26.5+/-7.6 years). After induction of light hypnosis, anxiety and then relaxation was suggested using a standardized text (reverse sequence in half of the subjects). Nineteen-channel, eyes-closed EEG (20 artifact-free s/subject) was analyzed (source localization using FFT approximation and low resolution electromagnetic tomography, LORETA). Global tests revealed the strongest difference (P<0.005) between EEG source gravity center locations during the two emotional states in the excitatory beta-2 EEG frequency band (18.5-21 Hz). Post hoc tests showed that the sources were located more right during anxiety than during relaxation (P=0.01). LORETA specified that anxiety showed maximally stronger activity than relaxation in right Brodmann area 10, and relaxation showed maximally stronger activity than anxiety in left Brodmann area 22. Clearly, the two induced emotional states were associated with activity of different neural populations. Our results agree with reports on brain activity shifted to the right (especially fronto-temporal) during negative compared with positive emotions, and support the role of beta-2 EEG frequency in emotional states.

Author information

Author/s: Isotani, T (T); Tanaka, H (H); Lehmann, D (D); Pascual-Marqui, R D (RD); Kochi, K (K); Saito, N (N); Yagyu, T (T); Kinoshita, T (T); Sasada, K (K);

Affiliation: The KEY Institute for Brain-Mind Research, University Hospital of Psychiatry, Lenggstrasse 31, CH-8029, Zurich, Switzerland. isotani(-atsign-)takii.kmu.ac.jp

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: International journal of psychophysiology : official journal of the International Organization of Psychophysiology (Int J Psychophysiol), published in Netherlands. (Language: eng)

Reference: 2001-Jun; vol 41 (issue 2) : pp 143-53

Dates: Created 2001/04/30; Completed 2001/06/28; Revised 2006/11/15;

PMID: 11325459, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult Anxiety Beta Rhythm Brain - physiology Brain Mapping Dominance, Cerebral Electroencephalography

Electroencephalography Female Humans Hypnosis Magnetoencephalography Male Relaxation - physiology

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