Research article summary (published 30 Aug 2002):

Glucose lowering efficacy of Ficus racemosa bark extract in normal and alloxan diabetic rats.

Full Abstract

The glucose-lowering efficacy of a methanol extract of the stem bark of Ficus racemosa Linn. (MEBFR) (Family Moraceae) was evaluated both in normal and alloxan-induced diabetic rats. The MEBFR at the doses examined (200 and 400 mg/kg p.o.) exhibited significant hypoglycaemic activity in both experimental animal models when compared with the control group. The activity was also comparable to that of the effect produced by a standard antidiabetic agent, glibenclamide 10 mg/kg. The present investigation established pharmacological evidence to support the folklore claim that it is an antidiabetic agent. Copyright 2002 John Wiley & Sons, Ltd.

Author information

Author/s: Bhaskara Rao, R (R); Murugesan, T (T); Sinha, Sanghamitra (S); Saha, B P (BP); Pal, M (M); Mandal, Subhash C (SC);

Affiliation: Department of Pharmaceutical Technology, Jadavpur University, Calcutta-700 032, India.

Journal and publication information

Publication Type: Comparative Study; Journal Article

Journal: Phytotherapy research : PTR (Phytother Res), published in England. (Language: eng)

Reference: 2002-Sep; vol 16 (issue 6) : pp 590-2

Dates: Created 2002/09/18; Completed 2002/12/09; Revised 2006/11/15;

PMID: 12237822, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals Blood Glucose - drug effects Diabetes Mellitus, Experimental - blood; drug therapy; mortality Ficus Glyburide - pharmacology Hypoglycemic Agents - pharmacology Lethal Dose 50

Lethal Dose 50 Plant Bark - chemistry Plant Extracts - pharmacology Rats Rats, Wistar Survival Rate Toxicity Tests

Associated Chemicals: Blood Glucose (0) ; Hypoglycemic Agents (0) ; Plant Extracts (0) ; Glyburide (10238-21-8)

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