Personality predicts working-memory-related activation in the caudal anterior cingulate cortex.

Full Abstract

Behavioral studies suggest that two affective dimensions of personality are associated with working memory (WM) function. WM load is known to modulate neural activity in the caudal anterior cingulate cortex (ACC), a brain region critical for the cognitive control of behavior. On this basis, we hypothesized that neural activity in the caudal ACC during a WM task should be associated with personality: correlated negatively with behavioral approach sensitivity (BAS) and positively with behavioral inhibition sensitivity (BIS). Using functional magnetic resonance imaging, we measured brain activity in 14 participants performing a three-back WM task. Higher self-reported BAS predicted better WM performance (r = .27) and lower WM-related activation in the caudal ACC (r = -.84), suggesting personality differences in cognitive control. The data bolster approach-withdrawal (action control) theories of personality and suggest refinements to the dominant views of ACC and personality.

Author information

Author/s: Gray, Jeremy R (JR); Braver, Todd S (TS);

Affiliation: Department of Psychology, Washington University, St. Louis, Missouri 63130, USA. jeremy_gray(-atsign-)post.harvard.edu

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal: Cognitive, affective & behavioral neuroscience (Cogn Affect Behav Neurosci), published in United States. (Language: eng)

Reference: 2002-Mar; vol 2 (issue 1) : pp 64-75

Dates: Created 2002/11/27; Completed 2003/01/13; Revised 2006/11/15;

PMID: 12452585, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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