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| Research article summary (published 29 Nov 2002): |
Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats.
Full Abstract
AIM OF THE STUDY: The main aim was to demonstrate the effects of Cassia auriculata flowers on blood glucose and lipid levels in experimental diabetic rats. METHODOLOGY: Aqueous extract of Cassia auriculata flowers was administered orally and different doses of the extract on blood glucose, haemoglobin, glycosylated haemoglobin, serum and tissue lipids, hexokinase and glucose-6-phosphatase in streptozotocin-induced diabetic rats were studied. Glibenclamide was used as standard reference drug. RESULTS: Cassia auriculata flower extract (CFEt), at doses of 0.15, 0.30 and 0.45 g/kg body weight for 30 days, suppressed the elevated blood glucose and lipid levels in diabetic rats. Cassia auriculata at 0.45 g/kg was found to be comparable to glibenclamide. CONCLUSION: Our findings indicate that the Cassia auriculata flowers possess antihyperlipidaemic effect in addition to antidiabetic activity.
Author information
Author/s: Pari, L (L); Latha, M (M);
Affiliation: Department of Biochemistry, Faculty of Science Annamalai University, Annamalai Nagar Tamil Nadu-608 002, India. Paribala(-atsign-)sancharnet.in
Journal and publication information
Publication Type: Comparative Study; Journal Article
Journal: Singapore medical journal (Singapore Med J), published in Singapore. (Language: eng)
Reference: 2002-Dec; vol 43 (issue 12) : pp 617-21
Dates: Created 2003/04/15; Completed 2003/06/11; Revised 2006/11/15;
PMID: 12693765, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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