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| Research article summary (published 29 Jun 2003): |
Lignans, phenylpropanoids and polyacetylenes from Chaerophyllum aureum L. (Apiaceae).
Full Abstract
Sub-aerial parts of Chaerophyllum aureum L. yielded two polyacetylenes, falcarinol (1), falcarindiol (2), three lignans, namely nemerosin (3), deoxypodorhizone (4), deoxypodo-phyllotoxin (5), two phenylpropanoids, 1'-hydroxymyristicin (6) and its angeloyl ester (7). Compounds 6 and 7 were isolated for the first time from plant material and their structures were elucidated by means of extensive 1- and 2-dimensional NMR spectroscopy and high resolution mass spectrometry. In bioautographic tests on TLC plates the dichloromethane extract showed a significant antimicrobial activity. Falcarindiol was identified as the main active principle whereas the phenylpropanoids and lignans showed no activity.
Author information
Author/s: Rollinger, Judith M (JM); Zidorn, Christian (C); Dobner, Michael J (MJ); Ellmerer, Ernst P (EP); Stuppner, Hermann (H);
Affiliation: Institut für Pharmazie, Abteilung Pharmakognosie, Universität Innsbruck, Josef-Moeller-Haus, Innrain 52, A-6020-Innsbruck, Austria. judith.rollinger(-atsign-)uibk.ac.at
Journal and publication information
Publication Type: Journal Article
Journal: Zeitschrift für Naturforschung. C, Journal of biosciences (Z Naturforsch C), published in Germany. (Language: eng)
Reference: -2003 Jul-Aug; vol 58 (issue 7-8) : pp 553-7
Dates: Created 2003/08/26; Completed 2003/10/21; Revised 2009/11/04;
PMID: 12939043, status: MEDLINE (last retrieval date: 11/4/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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