[The reaction to trichophytin in dermatophytoses]

(Contribuição ao estudo da reação à tricofitina nas dermatofitoses.)

Full Abstract

The authors investigated the specific immunological competence of 31 patients with dermatophytosis using tricophytin antigen. Among them, 54.8% showed reaction to the delay phase (48 h) in the following proportions: tinea inguinale, 75%; tinea pedis, 61.5%; tinea unguium, 50% and tinea corporis, 20%. Other 62.5% showed positive result to the early phase (30 m). The association between these reactions revealed that, although the majority of cases with early positive reaction showed negativity to the delayed reaction, 20.8% presented positively to both phases of the reaction. Out of the non-reactive patients to the delayed phase, 8 were submitted to the other cutaneous tests such as PPD, streptokinase, candidin, vaccinia and DNCB and showed preserved cellular immunity in 75%. These results suggest that, while using this reaction for immunological evaluation of patients with dermatophytosis, one should consider the overall immune status of the patient, the presence of early hypersensibility and the localization of the infection.

Author information

Author/s: Vilani-Moreno, F R (FR); de Arruda, M S (MS);

Affiliation: Instituto Lauro de Souza Lima, Bauru, SP, Brasil.

Journal and publication information

Publication Type: English Abstract; Journal Article; Research Support, Non-U.S. Gov't

Journal: Revista do Instituto de Medicina Tropical de São Paulo (Rev Inst Med Trop Sao Paulo), published in BRAZIL. (Language: por)

Reference: -1992 Nov-Dec; vol 34 (issue 6) : pp 505-9

Dates: Created 1994/02/03; Completed 1994/02/03; Revised 2006/11/15;

PMID: 1342118, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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