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| Research article summary (published 3 Sep 2003): |
Fast separation and determination of tyrosol, hydroxytyrosol and other phenolic compounds in extra-virgin olive oil by capillary zone electrophoresis with ultraviolet-diode array detection.
Full Abstract
Olive oil is the main source of fat in the Mediterranean diet, and its consumption has been related to a low incidence of coronary heart disease and certain cancers. Recent findings demonstrate that olive oil phenolics are powerful in vitro and in vivo antioxidants and display other biological activities that could partially account for the observed healthful effects of the Mediterranean diet. A detailed method optimization plan was carried out to separate the most popular phenols in olive oil for four separation parameters: buffer concentration, buffer pH, applied voltage and temperature. Consequently, an analytical method capable of separating 21 different phenols and polyphenols by capillary zone electrophoresis was developed; the separation was performed within 10 min, using a 40 cm x 50 microm capillary, with a 45 mM sodium tetraborate buffer (pH 9.60), at 27 kV and 30 degrees C. The optimized method was applied to methanolic extracts of several Italian extra-virgin olive oils obtained by different technologies in order to characterize and to compare their antioxidant profile. Positive correlations of phenolic compounds found by capillary zone electrophoresis (CZE) and two colorimetric indexes (total polyphenols and o-diphenols) were found and discussed.
Author information
Author/s: Bonoli, Matteo (M); Montanucci, Marina (M); Gallina Toschi, Tullia (T); Lercker, Giovanni (G);
Affiliation: Dipartimento di Scienze degli Alimenti, Università di Bologna, Via Ravennate 1020, Cesena 47023, Italy. mbonoli(-atsign-)foodsci.unibo.it
Journal and publication information
Publication Type: Journal Article
Journal: Journal of chromatography. A (J Chromatogr A), published in Netherlands. (Language: eng)
Reference: 2003-Sep; vol 1011 (issue 1-2) : pp 163-72
Dates: Created 2003/10/01; Completed 2004/06/11; Revised 2009/01/15;
PMID: 14518773, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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