 |
| Research article summary (published 24 May 2003): |
[Treatment of acute bipolar disorder. Intriguing balancing act between mania and depression]
(Therapie der akuten bipolaren Erkrankung. Kniffliger Balanceakt zwischen Manie und Depression.)
Full Abstract
The term bipolar disorder is no longer limited to the classical manic-depressive condition, but now subsumes a wide spectrum of illnesses. As a consequence of this expansion of the classification systems, the therapeutic utility of lithium and other mood stabilizing agents has to be defined anew. The majority treatment recommendations differentiate, symptom-related, between euphoric mania, mixed conditions, mania with psychotic symptoms and rapid cycling manic episodes. Current acute treatment includes, in addition to lithium, in particular carbamazepine and valproate, but also newer antiepileptic drugs such as lamotrigine or atypical neuroleptic agents such as olanzapine and risperidone. Due to the high suicidal risk, patients with bipolar depression often need to be given an antidepressant as well. It must, however, be remembered that in patients with rapid cycling, antidepressants may re-trigger mania.
Author information
Author/s: Grunze, H (H); Dittmann, S (S);
Affiliation: Psychiatrische Klinik, LMU München. heinz.grunze(-atsign-)psy.med.uni-muenchen.de
Journal and publication information
Publication Type: Comparative Study; English Abstract; Journal Article; Review
Journal: MMW Fortschritte der Medizin (MMW Fortschr Med), published in Germany. (Language: ger)
Reference: 2003-May; vol 145 Suppl 2 (issue ) : pp 27-30
Dates: Created 2003/10/28; Completed 2004/01/30; Revised 2008/11/21;
PMID: 14579481, status: MEDLINE (last retrieved date: 2/18/2009)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article
(including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MeSH Headings (categories) shown below.
Note: Bold headings indicate primary MeSH headings or qualifiers.
Associated Chemicals: Antidepressive Agents (0) ; Antimanic Agents (0) ; Antipsychotic Agents (0) ; Isotopes (0) ; Serotonin Antagonists (0) ; Serotonin Uptake Inhibitors (0) ; Triazines (0) ; Risperidone (106266-06-2) ; Benzodiazepines (12794-10-4) ; olanzapine (132539-06-1) ; Pirenzepine (28797-61-7) ; Carbamazepine (298-46-4) ; Lithium (7439-93-2) ; lamotrigine (84057-84-1) ; Valproic Acid (99-66-1)Related articles
These are the most related articles currently in our database:
- Comparison of the antimanic efficacy of carbamazepine and lithium carbonate by double-blind controlled study.
29 Apr 1990 - Algorithm for patient management of acute manic states: lithium, valproate, or carbamazepine? 30 Jan 1992
- Recent advances in treatment of acute mania. 30 Jan 1991
- Effects of carbamazepine on serum antidepressant concentrations in psychiatric patients. 29 Sep 1991
- Life events and the course of bipolar disorder. 30 Aug 1990
- Alternatives to lithium in the treatment of bipolar disorder. 30 Dec 1990
- Drugs for psychiatric disorders.
15 May 1991 - Lithium, benzodiazepines, and sexual function in bipolar patients. 30 May 1992
- Drugs for psychiatric disorders. 20 Oct 1976
- PDQ-R personality disorders in bipolar patients. 29 Nov 1991
Related Article Map
10/20/1976
5/30/1992
Higher Relevance Score (15)
Lower Relevance Score (12)
Legend: 
- FREE Full text Article. - Abstract only. - Title only. More help.
See a larger map of 100+ related articles.