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| Research article summary (published 30 Dec 2003): |
fMRI of healthy older adults during Stroop interference.
Full Abstract
The Stroop interference effect, caused by difficulty inhibiting overlearned word reading, is often more pronounced in older adults. This has been proposed to be due to declines in inhibitory control and frontal lobe functions with aging. Initial neuroimaging studies of inhibitory control show that older adults have enhanced activation in multiple frontal areas, particularly in inferior frontal gyrus, indicative of recruitment to aid with performance of the task. The current study compared 13 younger and 13 older adults, all healthy and well educated, who completed a Stroop test during functional magnetic resonance imaging. Younger adults were more accurate across conditions, and both groups were slower and less accurate during the interference condition. The groups exhibited comparable activation regions, but older adults exhibited greater activation in numerous frontal areas, including the left inferior frontal gyrus. The results support the recruitment construct and suggest, along with previous research, that the inferior frontal gyrus is important for successful inhibition.
Author information
Author/s: Langenecker, Scott A (SA); Nielson, Kristy A (KA); Rao, Stephen M (SM);
Affiliation: Department of Psychology and the Integrative Neuroscience Research Center, Marquette University, Milwaukee, WI, USA. slangen(-atsign-)umich.edu
Grants: M01 RR000058-445129 (Agency:NCRR NIH HHS) ; R01 AG022304-01 (Agency:NIA NIH HHS)
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: NeuroImage (Neuroimage), published in United States. (Language: eng)
Reference: 2004-Jan; vol 21 (issue 1) : pp 192-200
Dates: Created 2004/01/26; Completed 2004/03/26; Revised 2007/11/26;
PMID: 14741656, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: 18 Feb 2009 00:00:00)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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