Research article summary (published 30 Aug 2004):

[Usefulness of biological markers in the evaluation of smoking at the first visit of a smoking cessation program]

(Intérêt des principaux indicateurs du tabagisme lors de la première consultation de sevrage tabagique.)

Full Abstract

INTRODUCTION: We have studied the relationship between urinary cotinine and other tobacco markers to assess the relevance of urinary cotinine in the dosage of nicotine substitutes. METHODS: One hundred and fifty-five patients, who were regular cigarette smokers not taking any nicotine substitutes took part in the study. The parameters examined were daily consumption, nicotine contents of the cigarettes, the Fagerström test score, levels of carbon monoxide (CO) in exhaled breath air and urinary cotinine. RESULTS: The most significant correlation was between urinary cotinine and exhaled CO (Spearman rs=0,59 p<0,001). The correlation between urinary cotinine, the Fagerström test (rs=0,32 p<0,001) and daily cigarette consumption (rs=0,32 p<0,001) was less significant. The nicotine content was not related to urinary cotinine (rs =-0,10NS). CONCLUSIONS: For economic reasons measuring urinary cotinine is not necessary when the CO level is or=35 ppm. It becomes useful if the CO level is between 15 and 34 ppm, as CO level in itself is insufficient to determine the dosage of nicotine substitutes.

Author information

Author/s: Underner, M (M); Ingrand, P (P); Favreau, M (M); Mura, P (P); Meurice, J-C (JC);

Affiliation: Centre de Tabacologie, CHU de Poitiers. m.underner(-atsign-)chu-poitiers.fr

Journal and publication information

Publication Type: English Abstract; Journal Article

Journal: Revue des maladies respiratoires (Rev Mal Respir), published in France. (Language: fre)

Reference: 2004-Sep; vol 21 (issue 4 Pt 1) : pp 705-10

Dates: Created 2004/11/10; Completed 2005/02/17; Revised 2006/11/15;

PMID: 15536371, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

Comments and Corrections

CommentIn: Rev Mal Respir. 2004 Sep;21(4 Pt 1):675-8. (PMID: 15536365)

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Adolescent Adult Aged Biological Markers - analysis Breath Tests Carbon Monoxide - analysis Cotinine - urine Female France - epidemiology

Humans Male Middle Aged Nicotine - analysis Plants, Toxic Smoking - epidemiology; urine Smoking Cessation Tobacco - chemistry Tobacco Use Disorder - diagnosis; psychology

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Biological Markers (0) ; Cotinine (486-56-6) ; Nicotine (54-11-5) ; Carbon Monoxide (630-08-0)

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