Cerebrocerebellar networks during articulatory rehearsal and verbal working memory tasks.

Full Abstract

Converging evidence has implicated the cerebellum in verbal working memory. The current fMRI study sought to further characterize cerebrocerebellar participation in this cognitive process by revealing regions of activation common to a verbal working task and an articulatory control task, as well as regions that are uniquely activated by working memory. Consistent with our model's predictions, load-dependent activations were observed in Broca's area (BA 44/6) and the superior cerebellar hemisphere (VI/CrusI) for both working memory and motoric rehearsal. In contrast, activations unique to verbal working memory were found in the inferior parietal lobule (BA 40) and the right inferior cerebellum hemisphere (VIIB). These findings provide evidence for two cerebrocerebellar networks for verbal working memory: a frontal/superior cerebellar articulatory control system and a parietal/inferior cerebellar phonological storage system.

Author information

Author/s: Chen, S H Annabel (SH); Desmond, John E (JE);

Affiliation: Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Grants: MH60234 (Agency:NIMH NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal: NeuroImage (Neuroimage), published in United States. (Language: eng)

Reference: 2005-Jan; vol 24 (issue 2) : pp 332-8

Dates: Created 2005/01/03; Completed 2005/04/14; Revised 2007/11/14;

PMID: 15627576, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

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