Research article summary (published 4 Apr 2005):

Interactions of ferric ions with olive oil phenolic compounds.

Full Abstract

The ferric complexing capacity of four phenolic compounds, occurring in olives and virgin olive oil, namely, oleuropein, hydroxytyrosol, 3,4-dihydroxyphenylethanol-elenolic acid (3,4-DHPEA-EA), and 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde (3,4-DHPEA-EDA), and their stability in the presence of ferric ions were studied. At pH 3.5, all compounds formed a reversible 1:1 complex with ferric ions, but hydroxytyrosol could also form complexes containing >1 ferric ion per phenol molecule. At pH 5.5, the complexes between ferric ions and 3,4-DHPEA-EA or 3,4-DHPEA-EDA were relatively stable, indicating that the antioxidant activity of 3,4-DHPEA-EA or 3,4-DHPEA-EDA at pH 5.5 is partly due to their metal-chelating activity. At pH 7.4, a complex containing >1 ferric ion per phenol molecule was formed with hydroxytyrosol. Oleuropein, 3,4-DHPEA-EA, and 3,4-DHPEA-EDA also formed insoluble complexes at this pH. There was no evidence for chelation of Fe(II) by hydroxytyrosol or its derivatives. At all pH values tested, hydroxytyrosol was the most stable compound in the absence of Fe(III) but the most sensitive to the presence of Fe(III).

Author information

Author/s: Paiva-Martins, Fátima (F); Gordon, Michael H (MH);

Affiliation: Centro de Investigação em Química, Departamento de Química, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, no. 687, 4169-007 Porto, Portugal. mpmartin(-atsign-)fc.up.pt

Journal and publication information

Publication Type: Journal Article

Journal: Journal of agricultural and food chemistry (J Agric Food Chem), published in United States. (Language: eng)

Reference: 2005-Apr; vol 53 (issue 7) : pp 2704-9

Dates: Created 2005/03/30; Completed 2005/05/18;

PMID: 15796614, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Drug Stability Ferric Compounds - chemistry Hydrogen-Ion Concentration Phenols - chemistry

Phenols - chemistry Phenylethyl Alcohol - analogs & derivatives; chemistry Plant Oils - chemistry Pyrans - chemistry

Associated Chemicals: 3,4-dixydroxyphenylethanol elenolic acid (0) ; Ferric Compounds (0) ; Phenols (0) ; Plant Oils (0) ; Pyrans (0) ; 3,4-dihydroxyphenylethanol (10597-60-1) ; oleuropein (32619-42-4) ; Phenylethyl Alcohol (60-12-8) ; olive oil (8001-25-0)

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