Research article summary (published 30 May 2005):

Antidiabetic and antihyperlipemic effects of Clemeo felina.

Full Abstract

Petroleum ether and benzene extracts of Clemeo felina, given orally at doses of 300 mg kg(-1) day(-1) for 30 days, were found to be antidiabetic and antihyperlipemic on alloxan diabetic rats. Moreover, a significant decrease in the activities of serum enzymes like alkaline phosphatase, acid phosphatase and HMGCoA reductase activity in the liver was observed. However, treatment of rats with the extracts as well as standard antidiabetic drugs increased liver hexakinase activity and serum LDH activity.

Author information

Author/s: Nagarajan, N S (NS); Murugesh, N (N); Thirupathy Kumaresan, P (P); Radha, N (N); Murali, A (A);

Affiliation: Department of Chemistry, Gandhigram Rural Institute, Deemed University, Gandhigram 624 302, Tamil Nadu, India. nsndgj(-atsign-)yahoo.co.in

Journal and publication information

Publication Type: Comparative Study; Journal Article

Journal: Fitoterapia (Fitoterapia), published in Netherlands. (Language: eng)

Reference: 2005-Jun; vol 76 (issue 3-4) : pp 310-5

Dates: Created 2005/05/31; Completed 2005/08/15; Revised 2006/11/15;

PMID: 15885927, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article
(including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Animals Antilipemic Agents - chemistry; pharmacology Diabetes Mellitus, Experimental - drug therapy Glyburide - pharmacology Hypoglycemic Agents - chemistry; pharmacology

Insulin - pharmacology Male Plant Extracts - pharmacology Rats Rats, Wistar

Associated Chemicals: Antilipemic Agents (0) ; Hypoglycemic Agents (0) ; Plant Extracts (0) ; Glyburide (10238-21-8) ; Insulin (11061-68-0)

Related articles

These are the highest related articles currently in the database:

• Comparison between ethanolic and aqueous extracts from Chinese juniper berries for hypoglycaemic and hypolipidemic effects in alloxan-induced diabetic rats. 19 Sep 2007
• Hypoglycemic and hypolipidemic effects of alcoholic extract of Tribulus alatus in streptozotocin-induced diabetic rats: a comparative study with T. terrestris (Caltrop). 30 Aug 2007
• Antidiabetic properties of aqueous barks extract of Parinari excelsa in alloxan-induced diabetic rats. 7 Feb 2008
• Hypoglycaemic, antihyperglycaemic and hypolipidemic activities of Caesalpinia bonducella seeds in rats. 30 Aug 1997
• Mineral contents of aloe vera leaf gel and their role on streptozotocin-induced diabetic rats. 30 Dec 2004
• Anti-diabetic, anti-hyperlipidemic and spermatogenic effects of Amaranthus spinosus Linn. on streptozotocin-induced diabetic rats. 21 Aug 2007
• Dual PPAR-alpha and -gamma activators derived from novel benzoxazinone containing thiazolidinediones having antidiabetic and hypolipidemic potential. 26 Sep 2005
• The in vivo interaction between gliclazide and glibenclamide and insulin on glucose disposal in the rat. 29 Apr 1999
• Antihyperglycemic and hypolipidemic effects of Costus speciosus in alloxan induced diabetic rats. 29 Apr 2008
• Antidiabetic effect of a glycoside of pelargonidin isolated from the bark of Ficus bengalensis Linn. 30 Jul 1992

See 100+ related articles.

Related Article Map

Legend: - FREE Full text Article. - Abstract only. - Title only. More help.

See a large map of 100+ related articles.