Research article summary (published 30 May 2005):

Stimulus processing and associative learning in Wistar and WKHA rats.

Full Abstract

This study assessed basic learning and attention abilities in Wistar-Kyoto hyperactive (WKHA) rats using appetitive conditioning preparations. Two measures of conditioned responding to a visual stimulus, orienting behavior (rearing on the hind legs), and food cup behavior (placing the head inside the recessed food cup) were measured. In Experiment 1, simple conditioning, but not extinction, was impaired in WKHA rats compared with Wistar rats. In Experiment 2, nonreinforced presentations of the visual cue preceded the conditioning sessions. WKHA rats displayed less orienting behavior than Wistar rats but comparable levels of food cup behavior. These data suggest that WKHA rats exhibit specific abnormalities in attentional processing as well as in learning stimulus-reward relationships. (c) 2005 APA, all rights reserved.

Author information

Author/s: Chess, Amy C (AC); Keene, Christopher S (CS); Wyzik, Elizabeth C (EC); Bucci, David J (DJ);

Affiliation: Department of Psychology, University of Vermont, USA.

Grants: P20RR16462 (Agency:NCRR NIH HHS) ; R03 MH066941-01 (Agency:NIMH NIH HHS) ; R03MH066941 (Agency:NIMH NIH HHS) ; R21 MH069670-02 (Agency:NIMH NIH HHS) ; R21MH069670 (Agency:NIMH NIH HHS)

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal: Behavioral neuroscience (Behav Neurosci), published in United States. (Language: eng)

Reference: 2005-Jun; vol 119 (issue 3) : pp 772-80

Dates: Created 2005/07/06; Completed 2005/10/11; Revised 2008/11/20;

PMID: 15998198, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Animals Appetite - physiology Association Learning - physiology Attention - physiology Behavior, Animal Conditioning (Psychology) - physiology Cues Exploratory Behavior - physiology Extinction, Psychological - physiology

Extinction, Psychological - physiology Male Orientation - physiology Photic Stimulation - methods Rats Rats, Inbred WKY - physiology Rats, Wistar Reinforcement (Psychology) Statistics, Nonparametric

Note: Bold headings indicate primary MeSH headings or qualifiers.

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