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| Research article summary (published 30 Dec 2004): |
Hypoglycemic and antiperglycemic effects of Semecarpus anacardium linn in normal and alloxan-induced diabetic rats.
Full Abstract
The effect of ethanolic extract of dried nuts of Semecarpus anacardium on blood glucose level was investigated in both normal and alloxan induced diabetic rats. The blood glucose levels were measured at 0, 1, 2 and 3 hours after the treatment. The ethanolic extract of S. anacardium (100 mg/kg) reduced the blood glucose of normal rat from 84 +/- 1.4 to 67 +/- 1.7 mg/dl, 3 hours after oral administration of the extract (P < 0.05). It also significantly lowered blood glucose level in alloxan induced diabetic rat from 325 +/- 2.2 to 144 +/- 1.4 mg/dl, 3 hours after oral administration of the extract (P < 0.05). The antihyperglycemic activity of S. anacardium was compared with tolbutamide, an oral hypoglycemic agent.
Author information
Author/s: Kothai, R (R); Arul, B (B); Kumar, K Suresh (KS); Christina, A J M (AJ);
Affiliation: College of Pharmacy, Yercaud Main Road, Salem, Tamil Nadu, 636008, India.
Journal and publication information
Publication Type: Comparative Study; Journal Article
Journal: Journal of herbal pharmacotherapy (J Herb Pharmacother), published in United States. (Language: eng)
Reference: 2005-; vol 5 (issue 2) : pp 49-56
Dates: Created 2005/11/01; Completed 2006/02/14; Revised 2006/11/15;
PMID: 16260409, status: MEDLINE (last retrieved date: 2/18/2009)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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Associated Chemicals: Antioxidants (0) ; Blood Glucose (0) ; Hemoglobins (0) ; Hypoglycemic Agents (0) ; Plant Extracts (0) ; Alloxan (50-71-5) ; Tolbutamide (64-77-7)Related articles
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