Screening of plants used in Danish folk medicine to treat epilepsy and convulsions.

Full Abstract

Aqueous and ethanolic extracts of 42 plants used in Danish folk medicine for the treatment of epilepsy and convulsions, or for inducing sedation, were tested for affinity to the GABA(A)-benzodiazepine receptor in the flumazenil-binding assay. Ethanolic extracts of leaves of Primula elatior and Primula veris and aerial parts of Tanacetum parthenium exhibited good, dose-dependent affinity.

Author information

Author/s: Jäger, Anna K (AK); Gauguin, Bente (B); Adsersen, Anne (A); Gudiksen, Lene (L);

Affiliation: Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, 2 Universitetsparken, 2100 Copenhagen O, Denmark. ankj(-atsign-)dfuni.dk

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal: Journal of ethnopharmacology (J Ethnopharmacol), published in Ireland. (Language: eng)

Reference: 2006-Apr; vol 105 (issue 1-2) : pp 294-300

Dates: Created 2006/03/29; Completed 2006/12/22;

PMID: 16293381, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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