Research article summary (published 30 Mar 2006):

The role of neural activity in cortical axon branching.

Full Abstract

Axonal branching is an important process for establishing the final pattern of connections between a neuron and its target cells. Cortical connections between upper-layer cells in the neocortex have provided insights into the cellular mechanisms by which electrical activity regulates neural connectivity, including branch formation. Recent evidence further indicates that spontaneous firing and synaptic transmission contribute to axonal branching of cortical neurons through postsynaptic activation.

Author information

Author/s: Uesaka, Naofumi (N); Ruthazer, Edward S (ES); Yamamoto, Nobuhiko (N);

Affiliation: Neuroscience Laboratories, Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan.

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry (Neuroscientist), published in United States. (Language: eng)

Reference: 2006-Apr; vol 12 (issue 2) : pp 102-6

Dates: Created 2006/03/03; Completed 2006/05/22; Revised 2006/11/15;

PMID: 16514007, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Action Potentials - physiology Animals Axons - physiology; ultrastructure Cell Differentiation - physiology Cerebral Cortex - cytology; embryology; growth & development

Humans Neural Pathways - cytology; embryology; growth & development Organ Culture Techniques Receptors, Glutamate - metabolism Synaptic Transmission - physiology

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Receptors, Glutamate (0)

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