Treatment of cognitive impairment in multiple sclerosis.

Full Abstract

Cognitive impairment in multiple sclerosis is an increasingly recognized entity. This article reviews the cognitive impairment of multiple sclerosis, its prevalence, its relationship to different types of multiple sclerosis, and its contribution to long-term functional prognosis. The discussion also focuses on the key elements of cognitive dysfunction in multiple sclerosis which distinguish it from other forms of cognitive impairment. Therapeutic interventions potentially effective for the cognitive impairment of multiple sclerosis are reviewed including the effects of disease modifying therapies and the use of physical and cognitive interventions.

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Author information

Author/s: Pierson, Susan H (SH); Griffith, Nathan (N);

Affiliation: Drake Center, Department of Neurology, University of Cincinnati, 151 West Galbraith Road, Cincinnati, OH 45216, USA. SPierson(-atsign-)CapeCodHealth.org

Journal and publication information

Publication Type: Journal Article; Review

Journal: Behavioural neurology (Behav Neurol), published in Netherlands. (Language: eng)

Reference: 2006-; vol 17 (issue 1) : pp 53-67

Dates: Created 2006/05/24; Completed 2006/08/03;

PMID: 16720960, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adjuvants, Immunologic - therapeutic use
Cognition Disorders - diagnosis; etiology; rehabilitation; therapy
Cognitive Therapy - methods
Depression - complications; diagnosis; therapy
Fatigue - complications; diagnosis; therapy
Humans

Interferon-beta - therapeutic use
Multiple Sclerosis - classification; complications; psychology; therapy
Neuropsychological Tests
Peptides - therapeutic use
Quality of Life - psychology
Treatment Outcome

Associated Chemicals: Adjuvants, Immunologic (0) ; Peptides (0) ; copolymer 1 (0) ; interferon beta 1a (145258-61-3) ; Interferon-beta (77238-31-4)

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